Regulation of body weight and thermogenesis in seasonally acclimatized Brandt's voles (Microtus brandti)
Regulation of body weight and thermogenesis in seasonally acclimatized Brandt's voles (Microtus brandti)
复制标题
季节性适应的布氏田鼠（Microtus Brandti）的体重和产热调节
DOI：
10.1016/j.yhbeh.2005.04.004
复制
发表时间：
2005-09-01
影响因子：
3.5
通讯作者：
Wang, DH
中科院分区：
文献类型：
--
作者：
Li, XS;Wang, DH
动物形态、生理和行为的季节性变化被认为是生存和繁殖成功的适应策略。在本研究中，我们研究了体重和一些行为，生理，激素和生化标志物在季节性驯化的布氏田鼠（布氏田鼠），以检验我们的假设，布氏田鼠可以减少能量摄入与体重，体脂含量，血清瘦素水平下降，并在冬季条件下产热增加。布氏田鼠的体重在冬季（12月至次年2月）最低，春季和初夏（5月至6月）最高。体重的这种季节性变化与检查的其他标志物的变化有关。例如，冬季体重的下降伴随着能量摄入的增加和非颤抖性产热（NST）的增强，以及体脂量的减少和循环瘦素水平的降低。此外，瘦素循环水平与体重和体脂量呈正相关，与能量摄入和解偶联蛋白1含量呈负相关。总之，这些数据不支持我们的假设，并建议瘦素可能参与这一过程，并作为饥饿信号在布氏田鼠。(c)2005年爱思唯尔公司All rights reserved.
Seasonal changes in an animal's morphology, physiology, and behavior are considered to be an adaptive strategy for survival and reproductive success. In the present study, we examined body weight and several behavioral, physiological, hormonal, and biochemical markers in seasonally acclimatized Brandt's voles (Microtus brandti) to test our hypothesis that Brandt's voles can decrease energy intake associated with decrease in body weight, body fat content, serum leptin level, and increasing thermogenesis in winter conditions. We found that the body weight of Brandt's voles was lowest in winter (December to February) and highest in spring and early summer (May to June). This seasonal variation in body weight was associated with changes in other markers examined. For example, the winter decrease in body weight was accompanied by increased energy intake and enhanced nonshivering thermogenesis (NST) as well as by decreased body fat mass and reduced levels of circulating leptin. Further, circulating levels of leptin were positively correlated with body weight and body fat mass, and negatively correlated with energy intake and uncoupling protein 1 contents. Together, these data do not support our hypothesis and suggest that leptin may be involved in this process and serve as a starvation signal in Brandt's voles. (c) 2005 Elsevier Inc. All rights reserved.