Endolymphatic space size in patients with vestibular migraine and Meniere's disease
Endolymphatic space size in patients with vestibular migraine and Meniere's disease
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DOI：
10.1007/s00415-014-7458-9
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发表时间：
2014-11-01
影响因子：
6
通讯作者：
Nakashima, Tsutomu
中科院分区：
文献类型：
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作者：
Nakada, Takafumi;Yoshida, Tadao;Nakashima, Tsutomu
M,niSre 病 (MD) 的特点是阵发性眩晕、波动性听力损失和耳鸣。前庭性偏头痛 (VM) 是一种相对较新的疾病，其特征是阵发性眩晕或头晕、同时存在偏头痛和无听力损失。有时很难区分 VM 和伴有头痛的前庭 MD。由于内淋巴积水 (EH) 是 MD 的特征性体征，因此我们尝试评估这两种疾病的内淋巴空间大小。对 7 名 VM 患者和 7 名年龄和性别匹配的前庭 MD 患者的前庭和耳蜗内淋巴空间大小进行了评估。为了观察内淋巴空间，静脉注射钆造影剂 4 小时后，使用三维流体衰减反转恢复和阳性内淋巴信号反转图像和阳性外淋巴信号原始图像技术的 HYbriD 进行 3T 磁共振成像。在VM患者的前庭中，除两名单侧或双侧EH的患者外，未观察到EH。相比之下，在患有前庭MD的患者的前庭中，所有患者均具有显着的双侧或单侧EH。这些结果表明，VM 和前庭 MD 患者的内淋巴空间大小存在显着差异。
M,niSre's disease (MD) is characterized by episodic vertigo, fluctuating hearing loss and tinnitus. Vestibular migraine (VM) is a relatively new disorder that is characterized by episodic vertigo or dizziness, coexisting migraine and absence of hearing loss. It is occasionally difficult to distinguish between VM and vestibular MD with headache. Because endolymphatic hydrops (EH) is a characteristic sign of MD, we attempted to evaluate endolymphatic space size in both diseases. Endolymphatic space size in the vestibule and the cochlea was evaluated in seven patients with VM and in seven age- and sex-matched patients with vestibular MD. For visualization of the endolymphatic space, 3T magnetic resonance imaging was taken 4 h after intravenous injection of gadolinium contrast agents using three-dimensional fluid-attenuated inversion recovery and HYbriD of reversed image of positive endolymph signal and native image of positive perilymph signal techniques. In the vestibule of VM patients, EH was not observed, with the exception of two patients with unilateral or bilateral EH. In contrast, in the vestibule of patients with vestibular MD, all patients had significant EH, bilaterally or unilaterally. These results indicate that endolymphatic space size is significantly different between patients with VM and vestibular MD.