Comb-push ultrasound shear elastography (CUSE) with various ultrasound push beams.
Comb-push ultrasound shear elastography (CUSE) with various ultrasound push beams.
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DOI：
10.1109/tmi.2013.2257831
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发表时间：
2013-08
影响因子：
10.6
通讯作者：
Chen S
中科院分区：
文献类型：
--
作者：
Song P;Urban MW;Manduca A;Zhao H;Greenleaf JF;Chen S
梳推超声剪切弹性成像（CUSE）最近已被证明是一种快速和准确的二维（2D）弹性成像技术，可以提供一个完整的视野（FOV）剪切波速度图，只有一个快速的数据采集。CUSE的最初版本被称为U-CUSE，因为使用了未聚焦的超声推束。在本文中，我们提出了两个新版本的CUSE -聚焦CUSE（F-CUSE）和Marching CUSE（M-CUSE），它们使用聚焦超声推动波束来提高声辐射力穿透并在深层组织（例如肾脏和肝脏）中产生更强的剪切波。F-CUSE将换能器元件分为几个子组，这些子组同时发射多个聚焦超声束。M-CUSE为每个聚焦的推射束使用更多的元件，并使推射束横向行进。F-CUSE和M-CUSE都可以生成在每个成像像素位置处具有剪切波运动的梳状剪切波场，使得可以仅用一次数据采集来重建完整FOV 2D剪切波速度图。均匀体模实验表明，U-CUSE，F-CUSE和M-CUSE都可以产生光滑的剪切波速度图，准确的剪切波速度估计。夹杂物体模实验表明，所有CUSE方法都可以提供夹杂物和具有尖锐边界的背景之间的良好对比度，而F-CUSE和M-CUSE需要更短的推动持续时间来实现剪切波速度图，其SNR与U-CUSE相当。一个更具有挑战性的夹杂物体模实验与一个非常坚硬和深的夹杂物表明，更好的剪切波穿透可以通过使用F-CUSE和M-CUSE。最后，一个浅夹杂物实验表明，在近场的U-CUSE和F-CUSE可以实现良好的夹杂物形状的简化。安全性测量结果表明，所有CUSE方法的所有安全性参数均低于FDA监管限值。这些有希望的结果表明，使用各种推束，CUSE能够重建一个2D全FOV剪切弹性地图，仅使用一个推检测数据采集在广泛的深度范围内的软组织弹性成像。
Comb-push Ultrasound Shear Elastography (CUSE) has recently been shown to be a fast and accurate two-dimensional (2D) elasticity imaging technique that can provide a full field-of- view (FOV) shear wave speed map with only one rapid data acquisition. The initial version of CUSE was termed U-CUSE because unfocused ultrasound push beams were used. In this paper, we present two new versions of CUSE – Focused CUSE (F-CUSE) and Marching CUSE (M-CUSE), which use focused ultrasound push beams to improve acoustic radiation force penetration and produce stronger shear waves in deep tissues (e.g. kidney and liver). F-CUSE divides transducer elements into several subgroups which transmit multiple focused ultrasound beams simultaneously. M-CUSE uses more elements for each focused push beam and laterally marches the push beams. Both F-CUSE and M-CUSE can generate comb-shaped shear wave fields that have shear wave motion at each imaging pixel location so that a full FOV 2D shear wave speed map can be reconstructed with only one data acquisition. Homogeneous phantom experiments showed that U-CUSE, F-CUSE and M-CUSE can all produce smooth shear wave speed maps with accurate shear wave speed estimates. An inclusion phantom experiment showed that all CUSE methods could provide good contrast between the inclusion and background with sharp boundaries while F-CUSE and M-CUSE require shorter push durations to achieve shear wave speed maps with comparable SNR to U-CUSE. A more challenging inclusion phantom experiment with a very stiff and deep inclusion shows that better shear wave penetration could be gained by using F-CUSE and M-CUSE. Finally, a shallow inclusion experiment showed that good preservations of inclusion shapes could be achieved by both U-CUSE and F-CUSE in the near field. Safety measurements showed that all safety parameters are below FDA regulatory limits for all CUSE methods. These promising results suggest that, using various push beams, CUSE is capable of reconstructing a 2D full FOV shear elasticity map using only one push-detection data acquisition in a wide range of depths for soft tissue elasticity imaging.