Comparison of treatment adherence outcome among PLHIV enrolled in economic strengthening program with community control
Comparison of treatment adherence outcome among PLHIV enrolled in economic strengthening program with community control
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DOI：
10.1080/09540121.2017.1371667
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发表时间：
2018-01-01
影响因子：
1.7
通讯作者：
Grede, Nils
中科院分区：
文献类型：
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作者：
Bezabih, Tsegazeab;Weiser, S. D.;Grede, Nils
加强经济的干预措施越来越多地得到推广，以支持在资源匮乏的环境中艾滋病毒感染者的经济福祉和粮食安全。本研究旨在评估埃塞俄比亚旨在解决贫困和粮食不安全问题的ES干预措施对抗逆转录病毒治疗（ART）依从性的影响。采用比较横断面设计，比较受益于粮食计划署埃塞俄比亚ES项目的粮食不安全的艾滋病毒感染者与不参加ES项目的粮食不安全的艾滋病毒感染者之间的治疗依从性。使用视觉模拟量表（VAS）来衡量ART依从性，只有9.9%的ES组报告依从性低于95%，而对照组为25.9%。使用逻辑回归模型控制社会经济和人口统计学变量，参与ES活动的可能性增加了95%或更高的ART依从性，分别为2.4和5.6倍（通过VAS和ACTG方法测量），与未参与ES的PLHIV患者相比。研究结果表明，参与ES有助于改善粮食不安全的艾滋病毒感染者的抗逆转录病毒治疗依从性。如果进一步的研究验证了这一结果，ES应作为一个关键的战略，以提高艾滋病毒治疗的依从性在资源匮乏的环境中，坚持是一个令人关注的问题。
Economic strengthening (ES) interventions are increasingly promoted to support the economic well-being and food security of people living with HIV (PLHIV) in resource poor settings. This study aims to assess the impact of ES interventions in Ethiopia designed to address poverty and food insecurity on antiretroviral treatment (ART) adherence. A comparative cross-sectional design was employed to compare treatment adherence between food insecure PLHIV benefitting from the ES project of WFP Ethiopia to food insecure PLHIV not participating in ES. Using the visual analogue scale (VAS) to measure ART adherence, only 9.9% of the ES group reported less than 95% adherence compared to 25.9% of the comparison group. Controlling for socio-economic and demographic variables using logistic regression models, engagement in ES activities increased the likelihood of having 95% or greater ART adherence by a factor of 2.4 and 5.6 respectively (as measured by VAS and ACTG approaches) compared to those PLHIV that were not engaged in ES. The findings of the study suggest that engagement in ES contributes to improved ART adherence among food insecure PLHIV. If further studies validate this result, ES should be adopted as a key strategy to improve HIV treatment adherence in resource poor settings where adherence is an issue of concern.