Efficient Acylation of Anisole over Hierarchical Porous ZSM‐5 Structure
Efficient Acylation of Anisole over Hierarchical Porous ZSM‐5 Structure
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多级多孔 ZSM-5 结构上苯甲醚的高效酰化
DOI：
10.1002/ceat.200900542
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发表时间：
2010
影响因子：
2.1
通讯作者：
Li
中科院分区：
文献类型：
--
作者：
A. Padmanabhan;R. Selvin;Hsiu;Li
傅克酰化是制备芳香酮最重要的方法之一，芳香酮用于制造精细和特种化学品以及药物。在此，我们报道了一种使用分级多孔 ZSM-5 催化剂，用乙酸酐对苯甲醚进行酰化的高效且便捷的方法。以丁苯橡胶(SBR)为大孔模板合成了多级孔ZSM-5催化剂。通过 XRD、SEM 和 FT-IR 分析对催化剂的结构特征进行了表征。详细研究了温度、摩尔比和催化剂重量对苯甲醚酰化反应的影响。苯甲醚与乙酸酐摩尔比、催化剂重量和反应温度等反应参数分别优化为5:1、0.2 g和70℃。这里描述的方法对环境无害，并用高活性和可重复使用的催化剂代替了传统的催化剂。
Friedel-Crafts acylation is one of the most important methods to prepare aromatic ketones which are used in manufacturing fine and speciality chemicals, as well as pharmaceuticals. Herein, we report an efficient and convenient procedure for the acylation of anisole with acetic anhydride, using a hierarchical porous ZSM-5 catalyst. The hierarchical porous ZSM-5 catalyst was synthesized using styrene butadiene rubber (SBR) as macroporous template. The catalysts were characterized for their structural features by using XRD, SEM, and FT-IR analyses. The effect of temperature, molar ratio, and catalyst weight on the acylation of anisole was studied in detail. The reaction parameters such as anisole-to-acetic anhydride mole ratio, catalyst weight, and reaction temperature were optimized as 5:1, 0.2 g, and 70 °C, respectively. The method described here is environmentally benign and replaces the conventional catalyst by a highly active and reusable catalyst.