NEW SPONGIAN DITERPENOIDS FROM A GREAT-BARRIER-REEF SPONGE, SPONGIA SP
NEW SPONGIAN DITERPENOIDS FROM A GREAT-BARRIER-REEF SPONGE, SPONGIA SP
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DOI：
10.1021/jo00003a057
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发表时间：
1991-02-01
影响因子：
3.6
通讯作者：
SCHMITZ, FJ
中科院分区：
文献类型：
--
作者：
GUNASEKERA, SP;SCHMITZ, FJ
从大堡礁采集的一种海绵中分离出4个新的海绵二萜化合物，即4-6和8。 其中两种二萜具有环A内酯，而不是传统的环己烷环。 主要通过质子和碳-13 NMR分析确定结构。 其中一种代谢产物对小鼠白血病细胞具有轻微细胞毒性。
Four new spongian diterpenes, 4-6 and 8, have been isolated from a Spongia sp. of sponge collected on the Great Barrier Reef. Two of the diterpenes have ring-A lactones instead of the conventional cyclohexane rings. Structures were determined primarily by proton and carbon-13 NMR analyses. One of the metabolites is slightly cytotoxic to murine leukemia cells.