The Neurobiology of Childhood Structural Brain Development: Conception Through Adulthood
The Neurobiology of Childhood Structural Brain Development: Conception Through Adulthood
复制标题
DOI：
10.1007/7854_2013_265
复制
发表时间：
2014-01-01
期刊：
影响因子：
--
通讯作者：
Sowell, Elizabeth R.
中科院分区：
文献类型：
--
作者：
Houston, Suzanne M.;Herting, Megan M.;Sowell, Elizabeth R.
对人脑功能和结构的研究可以追溯到几个世纪前，当时哲学家和医生对特定认知功能的定位以及潜在脑组织的结构和组织进行了理论推导。近年来，磁共振成像(MRI)等非侵入性技术的出现为科学家提供了前所未有的机会，不仅可以加深我们对结构和功能的理解，还可以加深我们对典型和非典型儿童和成人群体中大脑发育轨迹的了解。在这一章中，我们希望提供一种系统水平的方法来介绍我们从受孕到成年所学到的关于结构性大脑发育的知识。我们讨论了核磁共振研究的重要发现，以及未来成像研究可以采取的方向，共同努力增强我们对大脑发育的理解，从而增强我们为各种神经发育障碍开发干预措施的能力。
The study of the function and structure of the human brain dates back centuries, when philosophers and physicians theorized about the localization of specific cognitive functions and the structure and organization of underlying brain tissue. In more recent years, the advent of non-invasive techniques such as Magnetic Resonance Imaging (MRI) has allowed scientists unprecedented opportunities to further our understanding not only of structure and function, but of trajectories of brain development in typical and a-typical child and adult populations. In this chapter, we hope to provide a system-level approach to introduce what we have learned about structural brain development from conception through adulthood. We discuss important findings from MRI studies, and the directions that future imaging studies can take in the concerted effort to enhance our understanding of brain development, and thus to enhance our ability to develop interventions for various neurodevelopmental disorders.