A new synthetic approach to phenol derivatives: use of ring-closing olefin metathesis.
A new synthetic approach to phenol derivatives: use of ring-closing olefin metathesis.
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DOI：
10.1002/chin.200548076
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发表时间：
2005-07
影响因子：
15
通讯作者：
Kazuhiro Yoshida;T. Imamoto
中科院分区：
文献类型：
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作者：
Kazuhiro Yoshida;T. Imamoto
苯酚衍生物是有机化学中最重要的一类芳香族化合物，采用钌催化1,4,7-三烯-3-酮的合环烯烃复合反应（RCM）合成了具有多种取代图的苯酚衍生物。以1,5,7-三烯-3- 1为前驱体的RCM反应制备苯酚衍生物也取得了成功。用常规方法制备的酚类化合物大多不容易得到。
Phenol derivatives, which are one of the most important classes of aromatic compounds in organic chemistry, were synthesized by ruthenium-catalyzed ring-closing olefin metathesis (RCM) of 1,4,7-trien-3-ones with versatile substitution patterns. The RCM reaction for producing phenol derivatives was also successful with 1,5,7-trien-3-one as another precursor. Most of the phenols prepared here could not be obtained easily by conventional methods.