Hetero Diels-Alder reaction of olefin with o-quinone methides generated using (±)-binolphosphoric acid for the stereoselective synthesis of 2,4-diarylbenzopyrans: application to the formal synthesis of myristinin B/C
Hetero Diels-Alder reaction of olefin with o-quinone methides generated using (±)-binolphosphoric acid for the stereoselective synthesis of 2,4-diarylbenzopyrans: application to the formal synthesis of myristinin B/C
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DOI：
10.1039/c3ra43526a
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发表时间：
2013-01-01
期刊：
影响因子：
3.9
通讯作者：
Vuram, Prasanna K.
中科院分区：
文献类型：
--
作者：
Gharpure, Santosh J.;Sathiyanarayanan, A. M.;Vuram, Prasanna K.
以(+/-)-二苯基磷酸为原料，通过烯烃与邻苯二酚甲醚(o-QMS)的Diels-Alder反应，实现了2，4-二芳基苯并吡喃的立体选择性合成。将该方法应用于肉豆蔻菌素B/C的合成。
Hetero Diels-Alder reaction of olefin with o-quinone methides (o-QMs) generated using (+/-)-binolphosphoric acid was developed for the stereoselective synthesis of 2,4-diarylbenzopyrans. The method thus developed was utilized in the formal synthesis of myristinin B/C.