Non-alcoholic fatty liver disease is independently associated with an increased prevalence of chronic kidney disease and proliferative/laser-treated retinopathy in type 2 diabetic patients
Non-alcoholic fatty liver disease is independently associated with an increased prevalence of chronic kidney disease and proliferative/laser-treated retinopathy in type 2 diabetic patients
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DOI：
10.1007/s00125-007-0897-4
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发表时间：
2008-03-01
期刊：
影响因子：
8.2
通讯作者：
Muggeo, M.
中科院分区：
文献类型：
--
作者：
Targher, G.;Bertolini, L.;Muggeo, M.
目的/假设非酒精性脂肪性肝病(NAFLD)与2型糖尿病心血管疾病风险增加相关。目前，非酒精性脂肪肝与糖尿病微血管并发症之间的关系缺乏相关信息。我们使用横断面设计评估了大量2型糖尿病患者中NAFLD与慢性肾脏疾病(CKD)和视网膜病变的相关性。方法视网膜病变(通过眼底镜)和CKD(定义为显性蛋白尿和/或估计的GFR)的患病率
Aims/hypothesis Non-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of cardiovascular disease in type 2 diabetes. Currently, there is a lack of information on associations between NAFLD and microvascular complications of diabetes. We assessed the associations between NAFLD and both chronic kidney disease (CKD) and retinopathy in a large cohort of type 2 diabetic individuals using a cross-sectional design.Methods Prevalence rates of retinopathy (by ophthalmoscopy) and CKD (defined as overt proteinuria and/or estimated GFR