Effect of the Helping Babies Breathe Program on Newborn Outcomes: Systematic Review and Meta-Analysis.
Effect of the Helping Babies Breathe Program on Newborn Outcomes: Systematic Review and Meta-Analysis.
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DOI：
10.3390/medicina58111567
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发表时间：
2022-10-31
期刊：
影响因子：
--
通讯作者：
Oliveros H
中科院分区：
文献类型：
--
作者：
Agudelo-Pérez S;Cifuentes-Serrano A;Ávila-Celis P;Oliveros H
背景和目的：在低收入和中等收入国家，新生儿死亡的主要原因是围产期窒息。新生儿复苏培训已被证明可以减少这一死亡原因。“帮助婴儿呼吸”方案是一个教授基本新生儿复苏术的方案，重点是经济资源有限的国家和地区。该研究的目的是确定实施HBB计划对新生儿结果的影响：死亡率和发病率。材料和方法：对观察性研究和临床试验进行了系统审查，这些研究和临床试验报告了在低收入和中等收入国家实施六溴代二苯方案对新生儿死亡率和发病率的影响。我们对提取的数据进行了荟萃分析。采用随机效应模型评价异质性，采用科克伦Q和I2检验，并按年龄和结局类型进行分层分析，以确定异质性的来源。结果：确定了11项研究。该方案的实施包括侧重于培训医生、护士、助产士和卫生专业学生的教育战略。极化结果显示总死亡率（OR 0.67; 95% CI 0.57，0.80）、分娩期死产死亡率（OR 0.62; 95% CI 0.51，0.75）和第一天死亡率（OR 0.70; 95% IC 0.64，0.77）降低。高异质性被发现，这在一定程度上解释了参与者的胎龄差异。结论：在低收入和中等收入国家实施HBB方案对降低早期新生儿死亡率具有重大影响。
Background and objectives: In low- and middle-income countries, the leading cause of neonatal mortality is perinatal asphyxia. Training in neonatal resuscitation has been shown to decrease this cause of mortality. The program “Helping Babies Breathe” (HBB) is a program to teach basic neonatal resuscitation focused on countries and areas with limited economic resources. The aim of the study was to determine the effect of the implementation of the HBB program on newborn outcomes: mortality and morbidity. Material and Methods: A systematic review was carried out on observational studies and clinical trials that reported the effect of the implementation in low- and middle-income countries of the HBB program on neonatal mortality and morbidity. We carried out a meta-analysis of the extracted data. Random-effect models were used to evaluate heterogeneity, using the Cochrane Q and I2 tests, and stratified analyses were performed by age and type of outcome to determine the sources of heterogeneity. Results: Eleven studies were identified. The implementation of the program includes educational strategies focused on the training of doctors, nurses, midwives, and students of health professions. The poled results showed a decrease in overall mortality (OR 0.67; 95% CI 0.57, 0.80), intrapartum stillbirth mortality (OR 0.62; 95% CI 0.51, 0.75), and first-day mortality (OR 0.70; 95% IC 0.64, 0.77). High heterogeneity was found, which was partly explained by differences in the gestational age of the participants. Conclusions: The implementation of the program HBB in low- and medium-income countries has a significant impact on reducing early neonatal mortality.
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影响因子：
3.8
作者：
Rule, Amy R. L.;Maina, Esther;Kamath-Rayne, Beena D.
通讯作者：
Kamath-Rayne, Beena D.
DOI：
10.1111/1552-6909.12019
发表时间：
2013-03-01
影响因子：
1.8
作者：
Steele, Carrie
通讯作者：
Steele, Carrie
DOI：
10.11124/jbisrir-2017-003535
发表时间：
2018-03-01
期刊：
JBI database of systematic reviews and implementation reports
影响因子：
--
作者：
Dol, Justine;Campbell-Yeo, Marsha;Richardson, Brianna
通讯作者：
Richardson, Brianna
影响因子：
8
作者：
Goudar, Shivaprasad S.;Somannavar, Manjunath S.;Singhal, Nalini
通讯作者：
Singhal, Nalini
影响因子：
168.9
作者：
Liu, Li;Oza, Shefali;Hogan, Dan;Chu, Yue;Perin, Jamie;Zhu, Jun;Lawn, Joy E.;Cousens, Simon;Mathers, Colin;Black, Robert E.
通讯作者：
Black, Robert E.