Electrocardiographic changes in patients with ischaemic stroke and their prognostic importance
Electrocardiographic changes in patients with ischaemic stroke and their prognostic importance
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DOI：
10.1111/j.1368-5031.2004.00010.x
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发表时间：
2004-05-01
影响因子：
2.6
通讯作者：
Akhan, G
中科院分区：
文献类型：
--
作者：
Dogan, A;Tunc, E;Akhan, G
由于证据有限，我们研究了心电图（ECG）变化对无原发性心脏病的缺血性卒中患者的预后重要性。这项研究由 162 名患者（92 名男性，年龄 64 +/- 14 岁）组成，他们在 18 个月内首次因缺血性中风入院就诊。通过缺血样心电图变化、长 QT 和心律失常来分析 1 个月死亡率。 79% 的中风患者观察到缺血样心电图改变，26% 的患者观察到长 QTc，44% 的患者观察到心律失常。早期死亡率为 27% (n = 44)。年龄、ST 段变化和异常 U 波是早期死亡率的单变量预测因子（每个 p < 0.05）。在多变量分析中，年龄 > 65 岁（OR = 1.4，p = 0.02）和 ST 段改变的存在（OR = 2.6，p = 0.0 1）只是独立的预测因素。虽然 ST 段变化在识别死亡风险患者方面的敏感性和特异性相对较低，但其阴性预测值为 82%。心电图变化常见于特定的缺血性卒中患者。无论起源如何，ST 段变化都可以预测早期死亡。
We investigated prognostic importance of electrocardiographic (ECG) changes in ischaemic stroke patients without primary heart disease because of the limited evidence. This study consisted of 162 patients (92 male, age 64 +/- 14 years) with first ischaemic stroke presenting to hospital during 18 months. One-month mortality was analysed by means of ischaemia-like ECG changes, long QT and arrhythmia. Ischaemia-like ECG changes were observed in 79% of stroke patients and long QTc in 26% and arrhythimas in 44%. Early mortality rate was 27% (n = 44). Age, ST-segment change and abnormal U wave were univariate predictors of early mortality (each p < 0.05). In multivariate analysis, age > 65 years (OR = 1.4, p = 0.02) and presence of ST-segment change (OR= 2.6, p = 0.0 1) were only independent predictors. Although sensitivity and specificity of ST-segment change were relatively low to identify patients at risk of death, its negative predictive value was 82%.The ECG changes are frequently seen in selected patients with ischaemic stroke. Regardless of origin, ST-segment change can be a predictor of early mortality.