The Future of Molecular Machines

The Future of Molecular Machines
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DOI:
10.1021/acscentsci.0c00064
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发表时间:
2020-03-25
影响因子:
18.2
通讯作者:
Aprahamian, Ivan
Aprahamian, Ivan
中科院分区:
化学1区
文献类型:
--
作者:
Aprahamian, Ivan

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几十年来,人工分子机器已经吸引了科学家和非科学家的想象力,因为它们具有改变和改善人类生活各个方面的明显潜力。在这篇展望中,我用自行车作为类比来解释分子机器是什么,在我看来,并通过一系列有代表性的案例研究来说明迄今为止所取得的重大成就,以及目前这些成就与该领域实现其巨大潜力之间的障碍。这种有意冷静的叙述希望能勾勒出一条通往丰富而令人兴奋的研究轨迹的道路,这条道路可能会挑战当前的从业者,并吸引年轻的科学家加入其中。考虑到我们在过去十年中所目睹的进展,我确信该领域的未来是光明的。
Artificial molecular machines have captured the imagination of scientists and nonscientists alike for decades now, given their clear potential to transform and enhance all aspects of human life. In this Outlook, I use a bicycle as an analogy to explain what a molecular machine is, in my opinion, and work through a representative selection of case studies to specify the significant accomplishments made to date, and the obstacles that currently stand between these and the field's fulfillment of its great potential. The hope of this intentionally sober account is to sketch a path toward a rich and exciting research trajectory that might challenge current practitioners and attract junior scientists into its fold. Considering the progress we have witnessed in the past decade, I am positive that the future of the field is a rosy one.