Substances derived from 4-ethyl octanoic acid account for primer pheromone activity for the "male effect" in goats
Substances derived from 4-ethyl octanoic acid account for primer pheromone activity for the "male effect" in goats
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DOI：
10.1292/jvms.65.1019
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发表时间：
2003-09-01
影响因子：
1.2
通讯作者：
Mori, Y
中科院分区：
文献类型：
--
作者：
Iwata, E;Kikusui, T;Mori, Y
特征性“山羊气味”的主要成分4-乙基辛酸（4 EOA）先前显示不具有引物信息素活性。我们自己的生物测定系统利用山羊下丘脑促性腺激素释放激素脉冲发生器的神经活动记录技术也证实了这一点。然而，当合成的4 EOA溶液在室温下保持数月时，引物信息素活性出现在相同的溶液中。顶空气相色谱/质谱分析表明，除了4个EOA样品具有引物信息素活性外，还有几种新形成的物质。这些结果表明，4 EOA衍生物是山羊的引物信息素，而不是4 EOA本身。
A major constituent of the characteristic "goaty odor" 4-ethyl octanoic acid (4EOA) was previously shown to have no primer pheromone activity. This was also confirmed by our own bioassay system utilizing the recording technique of neural activity of the hypothalamic gonadotropin-releasing hormone pulse generator in goats. However, when the synthetic 4EOA solution was kept at room temperature for several months, primer pheromone activity appeared in the same solution. Headspace gas chromatography/mass spectrometry analysis revealed that there were several newly formed substances in addition to 4EOA samples with primer pheromone activity. These results suggest that 4EOA derived substance(s) but not 4EOA itself is(are) primer pheromone in goats.