Serum ferritin-a novel risk factor in acute myocardial infarction.
Serum ferritin-a novel risk factor in acute myocardial infarction.
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DOI：
10.1016/s0019-4832(12)60056-x
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发表时间：
2012-03-01
影响因子：
1.5
通讯作者：
Suryawanshi, S D
中科院分区：
文献类型：
--
作者：
Holay, M P;Choudhary, A A;Suryawanshi, S D
目的：通过单因素和多因素分析研究血清铁蛋白与急性心肌梗死(AMI)的关系，探讨高血清铁蛋白与已有的常规危险因素的关系。方法：对75例急性心肌梗死(AMI)患者进行医院病例对照研究。结果：病例组血清铁蛋白中位数(2 2 0µg/L)显著高于对照组(15 5µg/L)(P≤0.0001)。在单因素分析中，除铁蛋白外，200µg/L(优势比[OR]6.71，95%可信区间[CI]=3.22-12.89，P
BACKGROUND: A possible association between body iron status and risk of coronary heart disease (CHD) has been found to be controversial from the data obtained from various studies.OBJECTIVES: To study the relationship of serum ferritin with acute myocardial infarction (AMI) in univariate and multivariate analysis and to assess the relationship of high serum ferritin with established conventional risk factors.METHODS: Hospital based case-control study of 75 cases of AMI, and 75 age and equal number of age, and gender-matched controls without having AMI in the age group of 30-70 years.RESULTS: Median serum ferritin levels were significantly higher in cases (220 mug/L) than controls (155 mug/L) (P ≤ 0.0001. In univariate analysis in addition to ferritin > 200 mug/L (odds ratio [OR] 6.71, 95% confidence interval [CI] = 3.22-12.89, P