Independent evaluator knowledge of treatment in a multicenter comparative treatment study of panic disorder.
Independent evaluator knowledge of treatment in a multicenter comparative treatment study of panic disorder.
复制标题
恐慌症多中心比较治疗研究中独立评估者的治疗知识。
DOI：
10.1038/sj.npp.1300373
复制
发表时间：
2004
期刊：
影响因子：
--
通讯作者：
Gorman,JackM
中科院分区：
文献类型：
--
作者：
Roll,David;Ray,SusanE;Marcus,SueM;Passarelli,Vincent;Money,Roy;Barlow,DavidH;Woods,ScottW;Shear,MKatherine;Gorman,JackM
本研究的目的是在惊恐障碍的多中心比较治疗研究中检查独立评估者（IE）对治疗条件的盲性。IE是15名心理学、社会工作和医学方面的博士和硕士级临床医生。他们对每位患者进行了三次治疗后评估。在每次评估访谈后，独立工程师立即填写一份表格，说明他们认为患者接受了五种可能治疗中的哪一种，以及为独立工程师提供有关患者治疗状况的任何具体信息。170名患者填写了这些表格。进行分析，以确定治疗后评估期间IE对治疗状况的猜测的准确性，IE猜测准确性与实际治疗分配之间的关系，准确猜测与结局评级之间的关系，以及破盲因素。一个显着的关系，发现IE猜测和实际治疗在所有三个评估点，跨个人IE，治疗网站，IE专业协会。IE对服用药物的患者的猜测并不比接受行为治疗的患者更准确。患者和项目工作人员无意中向IE提供了信息，提高了准确猜测的比率。这些研究结果的解释的治疗研究的影响进行了讨论，并提出建议，以改善失明的程序。
The purpose of this study was to examine independent evaluators'(IEs) blindness to treatment condition during a Multicenter Comparative Treatment Study of Panic Disorder. IEs were 15 doctoral-and masters-level clinicians in psychology, social work, and medicine. They conducted three post-treatment assessments with each patient. Immediately after each assessment interview, IEs completed a form indicating which of the five possible treatments they believed the patient had received and any specific information that provided IEs with information about a patient's treatment condition. These forms were completed for 170 patients. Analyses were conducted to determine the accuracy of guesses about treatment condition by IEs during post-treatment assessments, the relationship between accuracy of IE guessing and actual treatment assignment, the relationship between accurate guessing and outcome ratings, and contributors to the breaking of the blind. A significant relationship was found between IE guesses and actual treatment at all three assessment points, across individual IEs, treatment sites, and IE professional affiliations. IEs were no more accurate in their guessing about patients taking medication than those receiving behavior therapy. Patients and project staff inadvertently provided information to IEs that enhanced the rates of accurate guessing. Implications of these findings on interpretation of the treatment study are discussed, and recommendations are made for improving blindness procedures.