Daily Training efficiency during computerized cognitive rehabilitation training (CCRT): an analysis from a randomized trial in Ugandan children with and without severe malaria.
Daily Training efficiency during computerized cognitive rehabilitation training (CCRT): an analysis from a randomized trial in Ugandan children with and without severe malaria.
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DOI：
10.1080/09297049.2021.1962266
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发表时间：
2022-03
期刊：
影响因子：
--
通讯作者：
Giordani B
中科院分区：
文献类型：
--
作者：
Larrivey V;Neva J;Finn K;Sikorskii A;Familiar-Lopez I;Ucheagwu V;Ezeamama A;Ruisenor-Escudero H;Nakasujja N;Boivin M;Giordani B
乌干达儿童面临严重疟疾带来的严重认知后遗症的风险。计算机化认知康复训练（CCRT）代表了一种改善工作记忆、行为和执行功能的潜在方法，这些是严重疟疾后最危险的认知领域。本研究的主要目的是完成一项已结束的CCRT随机对照试验数据的二次分析，以比较常用的CCRT计划在滴定（适应性）或非滴定（非适应性）训练条件下的训练效率，以及疟疾严重程度增加的儿童，以确定各种因素如何影响CCRT的潜在改善。共有201名健康（n=102）或先前诊断患有严重或脑型疟疾（n=99）的学龄儿童（66.2%）被随机分为两个积极治疗组（滴定学习组和非滴定学习组）。每个孩子在八周内接受了24次一小时的训练，使用BrainTrain的Captain 's Log®CCRT，其中包括一套全面的CCRT任务。在24次训练中，儿童普遍受益于CCRT，但滴定的CCRT比未滴定的CCRT表现出明显的优势。疾病严重程度或BMI等因素，没有调节CCRT的表现指标。这些发现支持了我们的假设，即滴定CCRT会导致学习能力的急剧提高，但不支持我们的假设，即最近的重大疾病史会影响学习能力。这一发现在所有CCRT表现分数中都很明显，即使考虑到儿童通常来自农村、资源匮乏的环境，并且通常不熟悉计算机。
Children in Uganda are at risk for significant cognitive sequelae from severe malaria. Computerized cognitive rehabilitation training (CCRT) represents a potential method to improve working memory, behavior, and executive functioning, cognitive domains most at risk following severe malaria. The primary aim of this study was to complete a secondary analysis of data from a concluded CCRT randomized control trial in order to compare the training efficiency of a commonly used CCRT program under conditions of titrated (adaptive) or non-titrated (non-adaptive) training and with children with increasing malaria severity to determine how various factors may affect potential CCRT improvement. A total of 201 school-aged children (66.2% boys) who were either healthy (n=102) or previously diagnosed with severe or cerebral malaria (n=99) were randomized into two active treatment arms (titrated and non-titrated learning). Each child received 24 one-hour sessions of training over eight weeks using Captain’s Log® CCRT by BrainTrain, which includes a comprehensive set of CCRT tasks. Children generally benefited from CCRT over the 24 training sessions, but titrated CCRT showed a clear advantage over non-titrated. Severity of illness or factors such as BMI, did not moderate CCRT performance indicators. These findings support our hypothesis that titrated CCRT would result in steeper improvement in learning, but do not support our hypothesis that history of recent significant illness would affect learning proficiency. Findings were evident across all CCRT performance scores, even given that children were from generally rural, low-resource settings and were generally unfamiliar with computers.
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影响因子：
8.2
作者：
SCHMIDT, RA;BJORK, RA
通讯作者：
BJORK, RA
影响因子：
2.7
作者：
Boivin, MJ;Giordani, B;Ngunu, N
通讯作者：
Ngunu, N
DOI：
10.1097/00004583-200502000-00010
发表时间：
2005-02-01
影响因子：
13.3
作者：
Klingberg, T;Fernell, E;Westerberg, H
通讯作者：
Westerberg, H
影响因子：
11.8
作者：
Bangirana, Paul;Opoka, Robert O.;John, Chandy C.
通讯作者：
John, Chandy C.
影响因子：
3.6
作者：
Rabiner, David L.;Murray, Desiree W.;Malone, Patrick S.
通讯作者：
Malone, Patrick S.