Synthesis and use of α-diazo oxime ethers in the synthesis of ethylene diketone bis(O-methyloxime) derivatives
Synthesis and use of α-diazo oxime ethers in the synthesis of ethylene diketone bis(O-methyloxime) derivatives
复制标题
α-重氮肟醚的合成及其在乙烯二酮双(O-甲基肟)衍生物合成中的应用
DOI：
10.1002/jlac.1992199201144
复制
发表时间：
1992
影响因子：
2.8
通讯作者：
S. Bercovici
中科院分区：
文献类型：
--
作者：
S. Shatzmiller;S. Bercovici
肟醚4a-c的锂盐与甲磺酰基叠氮化物反应得到α-重氮肟醚5a-c。这些新化合物在高达90°C下是稳定的，然而，它们在Na 2CCl 4中热分解，并且在PdCl 2催化下以85- 91%的产率产生亚乙基二酮双（O-甲氧基肟）衍生物6a-c。介绍了5a-c的制备方法和特征光谱。
Reaction of the lithium salts of oxime ethers 4a–c with methanesulfonyl azide gives the α-diazo oxime ethers 5a–c. These novel compounds are stable up to 90°C, however, they decompose thermally in refluxing CCl4 and with PdCl2 catalysis to yield the ethylene diketone bis(O-methoxyloxime) derivatives 6a–c in yields of 85–91%. The preparation and characteristic spectral features of 5a–c are described.