Neuropsychological deficits and opiate abuse

Neuropsychological deficits and opiate abuse
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DOI:
10.1016/s0376-8716(02)00012-1
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发表时间:
2002-06-01
影响因子:
4.2
通讯作者:
McMillan, TM
McMillan, TM
中科院分区:
医学2区
文献类型:
--
作者:
Davis, PE;Liddiard, H;McMillan, TM

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使用一系列神经心理学测试对当前或过去有阿片类药物滥用史的人进行了认知功能检查。目前滥用阿片类药物的人中有60%在两项或两项以上的神经心理学测试中表现出至少两个标准差的损害,比没有药物滥用史的对照组明显更高。戒毒组与对照组比较差异无统计学意义。得出的结论是,阿片类药物滥用者的神经心理损害的风险更大,并恢复可能发生在禁欲。(C)2002爱思唯尔科学爱尔兰有限公司保留所有权利。
Cognitive functioning was examined in people with a current or past history of opiate abuse using a range of neuropsychological tests. Sixty percent of those currently abusing opiates showed impairments of at least two standard deviations from the published norms on two or more neuropsychological tests, a significantly higher incidence than found in matched controls with no history of drug abuse. The drug free group of recovering addicts fell between the other groups without significant differences. It was concluded that the risk of neuropsychological impairment is greater in opiate abusers, and that recovery may occur during abstinence. (C) 2002 Elsevier Science Ireland Ltd. All rights reserved.