The quantitation of triazolam in postmortem blood by gas chromatography/negative ion chemical ionization mass spectrometry.

The quantitation of triazolam in postmortem blood by gas chromatography/negative ion chemical ionization mass spectrometry.
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采用气相色谱/负离子化学电离质谱法定量死后血液中的三唑仑。

DOI:
10.1093/jat/10.6.241
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发表时间:
1986
影响因子:
2.5
通讯作者:
J. Wells
J. Wells
中科院分区:
医学3区
文献类型:
--
作者:
G. Koves;J. Wells

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以2 H6-三唑仑为内标,建立了一种特异、灵敏的测定死后血液中三唑仑含量的方法。三唑仑通过吸附在Amberlite XAD-2树脂上并随后用有机溶剂洗脱而从全血中分离。在负化学电离模式(Cl-)下使用选择离子监测(GC/MS/SIM)通过气相色谱/质谱法分析浸提液。该程序目前正在使用的情况下,工作和36例的结果。
A specific and sensitive assay has been developed to quantitate triazolam in postmortem blood using 2H6-triazolam as an internal standard. Triazolam is isolated from whole blood by adsorption on an Amberlite XAD-2 resin and subsequent elution with an organic solvent. The extract is analyzed by gas chromatography/mass spectometry using selected ion monitoring (GC/MS/SIM) in the negative chemical ionization mode (Cl-). The procedure is presently being used in case work and the results from 36 cases are presented.
三唑并苯二氮卓类药物阿普唑仑和三唑仑的电子捕获气相色谱分析。
DOI: 10.1016/s0378-4347(00)80261-3
发表时间: 1981
期刊: Journal of chromatography
影响因子: --
作者:
Greenblatt,DJ;Divoll,M;Moschitto,LJ;Shader,RI
通讯作者: Shader,RI