Prevalence of self-reported knee symptoms and management strategies among elderly individuals from Frederiksberg municipality: protocol for a prospective and pragmatic Danish cohort study
Prevalence of self-reported knee symptoms and management strategies among elderly individuals from Frederiksberg municipality: protocol for a prospective and pragmatic Danish cohort study
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DOI：
10.1136/bmjopen-2018-028087
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发表时间：
2019-09-01
期刊：
影响因子：
2.9
通讯作者：
Bliddal, Henning
中科院分区：
文献类型：
--
作者：
Ginnerup-Nielsen, Elisabeth Marie;Henriksen, Marius;Bliddal, Henning
2010年全球疾病负担研究将骨关节炎（OA）列为残疾生活年数的主要原因。随着人口老龄化，体重增加和久坐不动的生活方式，尤其是膝关节OA （KOA）预计会大幅增加。KOA的治疗策略包括非药物、药物和手术干预。与此同时，非处方止痛药因长期使用会带来一些风险而受到质疑。因此，运动和各种补充和替代药物（CAM）治疗关节疼痛的使用有所增加。可用的自我管理策略有很多，但没有关于它们在人口水平上的使用情况的概述，也没有关于它们是与医生的处方一起使用，还是替代医生的处方。本研究的目的是估计发生膝关节症状的人群发生率，并分析使用自我报告的预防措施与膝关节症状之间的关系（及其影响）。方法和分析本前瞻性队列研究从丹麦腓特烈斯堡市招募个体。所有年龄在60-69岁之间的公民将在10年内每年联系一次，并被要求参与一项基于网络的调查。主要结果是自我报告的膝关节症状及其与使用各种管理策略的关系，包括使用非药物治疗和辅助治疗。次要结局包括治疗对使用医疗保健系统和手术程序的影响。描述性和分析性统计（例如，逻辑回归）将用于提供样本和观察结果的总结以及自我管理与膝关节症状发展之间的关联。伦理与传播本研究可在未经卫生研究伦理委员会许可的情况下实施。已获得丹麦数据保护局的许可。研究结果将在同行评议的期刊上发表，并在相关会议上发表。
Introduction The Global Burden of Disease 2010 study ranked osteoarthritis (OA) as a leading cause of years lived with disability. With an ageing population, increasing body weight and sedentary lifestyle, a substantial increase especially in knee OA (KOA) is expected. Management strategies for KOA include non-pharmacological, pharmacological and surgical interventions. Meanwhile, over-the-counter pain medications have been discredited as they are associated with several risks with long-term usage. By consequence, the use of exercise and all sorts of complementary and alternative medicine (CAM) for joint pain has increased. The available self-management strategies are plenty, but there is no overview of their use at a population level and whether they are used along with doctors' prescriptions or replace these. The aim of this study is to estimate the population incidence of developing knee symptoms and analyse the association between (and impact of) the use of self-reported preventive measures and knee symptoms.Methods and analysis This prospective cohort study pragmatically recruits individuals from the municipality of Frederiksberg, Denmark. All citizens aged 60-69 years old will be contacted annually for 10 years and asked to participate in a web-based survey. The major outcomes are self-reported knee symptoms and their association with use of various management strategies, including use of non-pharmacological treatments and CAM. Secondary outcomes include the influence of treatments on use of healthcare system and surgical procedures. Descriptive and analytic statistics (eg, logistic regression) will be used to provide summaries about the sample and observations made and the associations between self-management and development of knee symptoms.Ethics and dissemination This study can be implemented without permission from the Health Research Ethics Committee. Permission has been obtained from the Danish Data Protection Agency. Study findings will be disseminated in peer-reviewed journals and presented at relevant conferences.