REVIEW OF LSD TREATMENT IN ALCOHOLISM
REVIEW OF LSD TREATMENT IN ALCOHOLISM
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DOI：
10.1159/000468273
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发表时间：
1971-01-01
期刊：
影响因子：
--
通讯作者：
ANDERSON, BJ
中科院分区：
文献类型：
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作者：
ABUZZAHAB, FS;ANDERSON, BJ
共有 31 项调查涉及 1,105 名患者，涉及 LSD 在治疗酗酒者中的作用。有 13 项无对照的单一大剂量研究，5 项有对照的此类研究，4 项无对照的多种低剂量 LSD 研究，3 项有对照的多项低剂量研究，以及 6 项不符合任何这些类别的杂项研究。单剂量范围为50至800μg，而多剂量范围（每单剂量）为25至800μg，总最大剂量为100-6,400μg（最多6剂）。随访时间从无到 65 个月不等。这种有争议的酗酒治疗方法的总体效果仍然令人失望。从具有不同设计和不同改进标准的各种已发表的研究中很难得出有意义的概括。
A total of 31 investigations involving 1,105 patients, on the effect of LSD in the treatment of alcoholics are reviewed. There were 13 single large-dose studies without controls, 5 such studies with controls, 4 studies of multiple low-dose LSD without controls,3 multiple low-dose studies with controls, and 6 miscellaneous investigations that did not fit any of these categories. Single doses ranged between 50 and 800 μg, while multiple doses ranged (per single dose) from 25 to 800 μg, with a total maximum dose of 100-6,400 μg(maximum of 6 doses). Follow-up ranged from none to 65 months. The overall effectiveness of this controversial treatment of alcoholics remains disappointing. It was difficult to reach meaningful generalizations from the variety of published investigations with different designs and variant criteria for improvement.