Risk Factors and Prevalence of Deep Vein Thrombosis After the 2016 Kumamoto Earthquakes

Risk Factors and Prevalence of Deep Vein Thrombosis After the 2016 Kumamoto Earthquakes
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DOI:
10.1253/circj.cj-18-1369
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发表时间:
2019-06-01
影响因子:
3.3
通讯作者:
Yamamoto, Tami
Yamamoto, Tami
中科院分区:
医学3区
文献类型:
--
作者:
Sato, Koji;Sakamoto, Kenji;Yamamoto, Tami

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背景:据报道,在历次地震之后,深静脉血栓(DVT)的发病率很高。我们通过在震中周围的各个疏散中心进行移动 DVT 筛查,检查了熊本地震疏散人员的 DVT 患病率和危险因素。方法和结果:2016 年 4 月 14 日熊本地震发生后 1 个月内,在 80 个疏散中心使用便携式超声检查(美国)进行了移动 DVT 筛查。对DVT阳性受试者进行问卷调查、体格检查和下肢超声检查,并进行简单的D-二聚体测量。受试者总数为 1,673 人,其中 178 人(10.6%)患有 DVT。在筛查期间,DVT 的患病率似乎逐渐下降,但 DVT 阳性组的年龄、安眠药物的使用、高血压、血脂异常、腿部水肿和小腿静脉曲张的患病率显着高于阴性组。在多变量逻辑回归分析中,高龄(≥ 70 岁)、使用安眠药物、小腿水肿和小腿静脉曲张是 DVT 的显着预测因素。在具有这4个预测因子的受试者中,DVT阳性率为71.4%。结论:在熊本地震发生后的第一个月,DVT的患病率和严重程度(以D-二聚体水平评估)随着时间的推移而下降。移动 DVT 筛查显示了疏散人员 DVT 风险分层的重要因素。
Background: After previous earthquakes, a high prevalence of deep vein thrombosis (DVT) has been reported. We examined DVT prevalence and risk factors in evacuees of the Kumamoto earthquakes by performing mobile DVT screening at various evacuation centers around the epicenter.Methods and Results: For 1 month after the Kumamoto earthquake on 14 April 2016, mobile DVT screening using portable ultrasonography (US) was performed at 80 evacuation centers. Questionnaires, physical examination, and US of the lower limb were carried out, and simple D-dimer measurements were undertaken for DVT-positive examinees. The total number of examinees was 1,673, of whom 178 (10.6%) had DVT. The prevalence of DVT seemed to be gradually decreasing in the screening period, but age, use of sleep medication, prevalence of hypertension, dyslipidemia, leg edema, and lower leg varix were significantly higher in the DVT positive group than in the negative group. On multivariable logistic regression analysis, high age (>= 70 years old), use of sleep medication, lower leg edema, and lower leg varix were significant predictors of DVT. In examinees with these 4 predictors, the DVT positive rate was 71.4%.Conclusions: In the first month after the Kumamoto earthquakes, DVT prevalence and severity, evaluated on D-dimer level, decreased with the passage of time. Mobile DVT screening indicated significant factors stratifying DVT risk in the evacuees.