Empirical Bayes Estimates for Large-Scale Prediction Problems.
Empirical Bayes Estimates for Large-Scale Prediction Problems.
复制标题
大规模预测问题的经验贝叶斯估计。
DOI:
10.1198/jasa.2009.tm08523
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发表时间:
2009-09-01
影响因子:
3.7
通讯作者:
Efron B
中科院分区:
文献类型:
--
作者:
Efron B
Classical prediction methods such as Fisher’s linear discriminant function were designed for small-scale problems, where the number of predictors N is much smaller than the number of observations n. Modern scientific devices often reverse this situation. A microarray analysis, for example, might include n = 100 subjects measured on N = 10,000 genes, each of which is a potential predictor. This paper proposes an empirical Bayes approach to large-scale prediction, where the optimum Bayes prediction rule is estimated employing the data from all the predictors. Microarray examples are used to illustrate the method. The results show a close connection with the shrunken centroids algorithm of, a frequentist regularization approach to large-scale prediction, and also with false discovery rate theory.
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影响因子:
56.9
作者:
Golub, TR;Slonim, DK;Lander, ES
通讯作者:
Lander, ES
影响因子:
1.5
作者:
Bickel, PJ;Levina, E
通讯作者:
Levina, E
影响因子:
3.7
作者:
EFRON, B;MORRIS, C
通讯作者:
MORRIS, C
影响因子:
5.7
作者:
Dudoit, S;Shaffer, JP;Boldrick, JC
通讯作者:
Boldrick, JC
影响因子:
5.7
作者:
Efron, Bradley
通讯作者:
Efron, Bradley