Microbiological factors influencing the outcome of nosocomial bloodstream infections: A 6-year validated, population-based model
Microbiological factors influencing the outcome of nosocomial bloodstream infections: A 6-year validated, population-based model
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DOI：
10.1086/513640
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发表时间：
1997-06-01
影响因子：
11.8
通讯作者：
Wenzel, RP
中科院分区：
文献类型：
--
作者：
Pittet, D;Li, N;Wenzel, RP
研究了1986年至1991年在一家拥有900张床位的三级保健医院发现的所有医院内血流感染患者（n = 1，745），以确定与感染死亡率独立相关的微生物因素。通过前瞻性、基于病例的监测和阳性血培养确定患者，并检查死亡率的长期趋势。采用单因素和多因素分析确定预后因素，并使用推导集和验证集。共有1，745例患者发生医院内血流感染，28天粗死亡率为22%，粗住院死亡率为35%。
All patients(n = 1,745) with nosocomial bloodstream infection identified between 1986 and 1991 at a single 900-bed tertiary care hospital were studied to identify microbiological factors independently associated with mortality due to the infection. Patients were identified by prospective, case-based surveillance and positive blood cultures, Mortality rates were examined for secular trends. Prognostic factors were determined with use of univariate and multivariate analyses, and both derivation and validation sets were used, A total of 1,745 patients developed nosocomial bloodstream infection, The 28-day crude mortality was 22%, and crude in-hospital mortality was 35%, Factors independently (all P