A 5-year follow-up of ambulatory blood pressure in healthy older adults
A 5-year follow-up of ambulatory blood pressure in healthy older adults
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DOI：
10.1016/s0895-7061(03)00906-3
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发表时间：
2003-08-01
影响因子：
3.2
通讯作者：
Guthrie, D
中科院分区：
文献类型：
--
作者：
Goldstein, IB;Shapiro, D;Guthrie, D
背景资料：本研究评估了5年的变化，在健康，老年人的动态血压（ABP），并确定在何种程度上可以预测从早期的BP措施和其他心血管风险factors.Methods：共162名男性和女性，年龄在55至79岁，没有以前的医疗疾病，完成了体检和两个24小时的ABP会议。这些受试者中有80%（130）在5年后重复了该程序。采用改进的分层回归分析来确定初始ABP和偶然血压（CBP）测量以及人口学和体格检查数据是否可以预测5年后的ABP。结果：5年后，清醒和睡眠期间的CBP和大多数ABP水平均升高。然而，73%的受试者的CBP保持在正常血压范围内。ABP变异性倾向于随时间降低。ABP和CBP测量值至少占5年后ABP水平预测方差的50%。相比之下，ABP变异性的可预测性相当低，特别是在睡眠期间（
Background: This study assessed 5-year changes in ambulatory blood pressure (ABP) in healthy, older individuals and determined the extent to which it could be predicted from earlier BP measures and other cardiovascular risk factors.Methods: A total of 162 men and women, aged 55 to 79 years, with no prior medical disorders, completed a medical examination and two 24-h ABP sessions. The procedures were repeated 5 years later in 80% (130) of these subjects. A modified hierarchical regression analysis was used to determine whether initial ABP and casual blood pressure (CBP) measures and demographic and physical examination data could predict ABP in 5 years.Results: The CBP and most ABP levels during waking and sleep increased after 5 years. However, CBP remained in the normotensive range for 73% of the subjects. The ABP variability tended to decrease over time. The ABP and CBP measures accounted for at least 50% of the variance in the prediction of ABP level after 5 years. In comparison, the predictability of ABP variability was quite low, particularly during sleep (