Creation and characterization of japanese standards for myocardial perfusion SPECT: Database from the Japanese society of nuclear medicine working group
Creation and characterization of japanese standards for myocardial perfusion SPECT: Database from the Japanese society of nuclear medicine working group
复制标题
DOI：
10.1007/s12149-007-0059-2
复制
发表时间：
2007-11-01
影响因子：
2.6
通讯作者：
Yokozuka, Koichi
中科院分区：
文献类型：
--
作者：
Nakajima, Kenichi;Kumita, Shinichiro;Yokozuka, Koichi
目的目前尚无适用于日本人群的心肌单光子发射计算机断层扫描（SPECT）标准。本研究的目的是建立日本核医学会批准的标准文件，并了解这一人群的心肌灌注模式的特点.方法在9家医院的合作下，共收集了326套运动-静息心肌灌注图像，来自心脏疾病可能性低的受试者。正常数据库包括具有360（n = 80）和180（n = 56）旋转的Tc-99 m-MIBI/替曲膦心肌灌注研究、具有360（n = 115）和180（n = 54）旋转的Tl-201研究以及具有360旋转的双同位素研究（n = 27）。结果成功地将多个中心的SPECT投影数据转换成一种通用的SPECT重建格式。当使用17段模型分析平均值时，间隔段中的心肌计数在180和360次旋转采集之间存在显著差异。男性和女性的下区和前区存在区域差异。Tc-99 m和Tl-201在某些节段中也观察到示踪剂差异。衰减模式显着不同的主题之间从美国和那些从Japanes.Conclusions心肌灌注数据，是特定的日本人口产生。正常数据库可以作为日本核心脏病学工作的标准。
Objective Standards for myocardial single- photon emission computed tomography (SPECT) adapted for a Japanese population were not available. The purpose of this study was to create standard fi les approved by the Japanese Society of Nuclear Medicine and to make known the characteristics of the myocardial perfusion pattern of this population.Methods With the collaboration of nine hospitals, a total of 326 sets of exercise - rest myocardial perfusion images were accumulated from subjects with a low likelihood of cardiac diseases. The normal database included a Tc-99m- MIBI/ tetrofosmin myocardial perfusion study with 360 (n = 80) and 180 (= 56) rotations, Tl-201 study with 360 (n = 115) and 180 rotations (n = 54) and a dual- isotope study with 360 rotation (n = 27). The projection images were transferred by digital imaging and communications in medicine (DICOM) format and reconstructed and analyzed with polar maps.Results The projection data from multiple centers were successfully transferred to a common format for SPECT reconstruction. When the average values were analyzed using a 17-segment model, myocardial counts in the septal segment differed signifi cantly between 180 and 360 rotation acquisitions. Regional differences were observed between men and women in the inferior and anterior regions. A tracer difference between Tc-99m and Tl-201 was also observed in some segments. The attenuation patterns differed signifi cantly between subjects from the United States and those from Japan.Conclusions Myocardial perfusion data that were specifi c for the Japanese population were generated. The normal database can serve a standard for nuclear cardiology work conducted in Japan.