SRC promotes lipogenesis: implications for obesity and breast cancer
SRC promotes lipogenesis: implications for obesity and breast cancer
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DOI:
10.1080/23723556.2020.1866975
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发表时间:
2021
期刊:
影响因子:
--
通讯作者:
Sheng-Cai Lin
中科院分区:
文献类型:
--
作者:
Shu-Yong Lin;Sheng-Cai Lin
Remodeling of lipid metabolism has been implicated in cancers; however, it remains obscure how the lipid metabolic pathways are altered by oncogenic signaling to affect tumor development. We have recently shown that proto-oncogene tyrosine-protein kinase Src interacts with and phosphorylates the lipogenesis enzyme phosphatidate phosphatase LPIN1 to promote breast cancer development.