Validity of the Hospital Anxiety and Depression Scale and the Beck Depression Inventory for use in end-stage renal disease patients
Validity of the Hospital Anxiety and Depression Scale and the Beck Depression Inventory for use in end-stage renal disease patients
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DOI：
10.1348/014466509x477827
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发表时间：
2010-11-01
影响因子：
3.1
通讯作者：
Honig, A.
中科院分区：
文献类型：
--
作者：
Loosman, W. L.;Siegert, C. E. H.;Honig, A.
目标。目的：验证医院焦虑抑郁量表(HADS)和贝克抑郁量表(BDI)在终末期肾病(ESRD)患者中的应用，并比较两种筛查方法的结果。横断面设计和受试者间设计。自变量为迷你国际神经精神病学访谈(MINI)诊断的抑郁症。以HADS和BDI总分为因变量。所有130名在阿姆斯特丹圣卢卡斯·安德烈亚斯医院接受血液透析(HD)或腹膜透析治疗的终末期肾病患者都符合这项研究的条件，并被要求同时填写HADS和BDI。将两种评定量表的结果与被视为金标准的基于MINI的重度抑郁发作的诊断进行比较。利用受试者工作特性曲线选择最佳截断值。在62名登记的受试者中，21人(34%)被诊断为抑郁障碍。最佳分界值为>；=12(HADS)和>；=13(BDI)。HADS和BDI的敏感性分别为81.0%和75.0%。两者的特异度均为90.2%。HADS和BDI都是诊断ESRD患者抑郁的有效筛查工具，但两种评定量表之间的差异无统计学意义。
Objective. To validate the Hospital Anxiety and Depression Scale (HADS) and the Beck Depression Inventory (BDI) for use in patients with end-stage renal disease (ESRD) and to compare the outcome of both screening measures with each other.Design. Cross-sectional and between-subjects design. The independent variable was the diagnosis depression by the Mini International Neuropsychiatric Interview (MINI). The dependent variables were the HADS and BDI total score.Methods. All 130 patients with ESRD who were treated with haemodialysis (HD) or peritoneal dialyses in the Sint Lucas Andreas Hospital in Amsterdam were eligible for this study and were asked to fill out both HADS and BDI. The outcomes of both rating scales were compared with the diagnosis major depressive episode based on the MINI, which was seen as the gold standard. Receiver operating characteristic curves were used to choose optimal cut-off values.Results. Of 62 enrolled subjects, 21 (34%) were diagnosed with a depressive disorder. Optimal cut-off values were >= 12 (HADS) and >= 13 (BDI). Sensitivity was 81.0% (HADS) and 75.0% (BDI). Specificity was 90.2% for both.Conclusions. Both HADS and BDI are valid screening instruments for the diagnosis depression in ESRD patients but there is no statistical difference found between both rating scales.