Subclinical carotid atherosclerosis and cognitive function
Subclinical carotid atherosclerosis and cognitive function
复制标题
DOI：
10.1111/j.1600-0404.2011.01538.x
复制
发表时间：
2011-08-01
影响因子：
3.5
通讯作者：
Mathiesen, E. B.
中科院分区：
文献类型：
--
作者：
Arntzen, K. A.;Mathiesen, E. B.
颈动脉粥样硬化是中风和随后的认知损害的主要危险因素。最近的研究表明，无临床卒中的颈动脉粥样硬化也可能是认知功能减退和痴呆的独立危险因素。超声是一种易于评估的非侵入性方法，可以测量颈动脉粥样硬化过程的不同阶段，被广泛应用于临床评估以及流行病学和临床研究。我们简要回顾了研究颈动脉亚临床动脉粥样硬化程度与认知功能和痴呆之间关系的研究，并讨论了几种可能的机制，可以解释动脉粥样硬化和认知损害之间的联系。
Carotid artery atherosclerosis is a major risk factor for stroke and subsequent cognitive impairment. Recent studies indicate that carotid atherosclerosis without clinical stroke may also be an independent risk factor for cognitive decline and dementia. Ultrasonography is an easily assessable and non-invasive method to measure different stages of the carotid artery atherosclerotic process and is widely used in clinical assessment as well as in epidemiological and clinical research. We give a brief review of studies that have investigated degrees of the subclinical atherosclerosis in the carotid arteries in relation to cognitive function and dementia, and we discuss several possible mechanisms that could explain the association between atherosclerosis and cognitive impairment.