A unified and quantitative network model for spatial attention in area V4
A unified and quantitative network model for spatial attention in area V4
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DOI：
10.1016/j.jphysparis.2009.11.006
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发表时间：
2010-01-01
影响因子：
--
通讯作者：
Jose, Jorge V.
中科院分区：
文献类型：
--
作者：
Hugues, Etienne;Jose, Jorge V.
视觉V4区的电生理实验表明，空间注意引起了许多神经活动的调制。根据刺激的特性，神经元的放电率增加或减少。在网络水平上，伽马频率范围（30 - 70 Hz）的振荡活动通过注意力而增强。最近，锥体神经元和中间神经元已被推测为不同的反应，但已被证明具有高的放电变异性。这些结果提出了问题的性质的调节注意输入V4和网络机制，导致这些不同的调制的出现。在这里，我们提出了一个V4的生物物理网络模型。我们首先再现神经活动观察到不同的刺激配置。我们发现，不同形式的注意力输入是可能的，这一事实可以解释所观察到的多样性的调制时，刺激对比度是不同的。我们的模型提供了一个统一的和定量的图片，从这些注意力调制所扮演的认知角色可以调查。(C)2009爱思唯尔有限公司保留所有权利。
Electrophysiological experiments in visual area V4 have shown that spatial attention induces a number of neural activity modulations. Depending on the stimulus characteristics, neuronal firing rates either increase or decrease. At the network level, the oscillatory activity in the gamma frequency range (30-70 Hz) is enhanced by attention. Recently, pyramidal neurons and interneurons have been surmised to respond differently, but have been shown to have both a high firing variability. These results raise the question of the nature of the modulatory attentional input to V4 and of the network mechanisms that lead to the emergence of these different modulations. Here, we propose a biophysical network model of V4. We first reproduce the neural activity observed in response to different stimulus configurations. We found that different forms of the attentional input are possible, and that this fact could explain the observed multiplicity of modulations when stimulus contrast is varied. Our model offers a unified and quantitative picture, from which the cognitive roles played by these attentional modulations can be investigated. (C) 2009 Elsevier Ltd. All rights reserved.