Antiparasitic Therapy
Antiparasitic Therapy
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DOI：
10.4065/mcp.2011.0203
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发表时间：
2011-06-01
影响因子：
8.9
通讯作者：
Blackburn, Brian G.
中科院分区：
文献类型：
--
作者：
Kappagoda, Shanthi;Singh, Upinder;Blackburn, Brian G.
寄生虫病影响着全球超过 20 亿人，造成大量发病率和死亡率，尤其是世界上最贫困人口。本概述重点关注人类主要原生动物和蠕虫感染的治疗。抗寄生虫治疗的最新进展包括扩大以青蒿素为基础的疟疾疗法、治疗土源性蠕虫和肠道原虫的新药、扩大恰加斯病患者抗寄生虫药物治疗的适应症，以及使用联合疗法治疗利什曼病和非洲人类锥虫病。
Parasitic diseases affect more than 2 billion people globally and cause substantial morbidity and mortality, particularly among the world's poorest people. This overview focuses on the treatment of the major protozoan and helminth Infections In humans. Recent developments in antiparasitic therapy include the expansion of artemisinin-based therapies for malaria, new drugs for soil-transmitted heiminths and intestinal protozoa, expansion of the indications for antiparasitic drug treatment in patients with Chagas disease, and the use of combination therapy for leishmaniasis and human African trypanosomiasis.