NON-MENDELIAN INHERITANCE OF MOSQUITO SUSCEPTIBILITY TO INFECTION WITH BRUGIA-MALAYI AND BRUGIA-PAHANGI
NON-MENDELIAN INHERITANCE OF MOSQUITO SUSCEPTIBILITY TO INFECTION WITH BRUGIA-MALAYI AND BRUGIA-PAHANGI
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DOI：
10.1126/science.7466401
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发表时间：
1981-01-01
期刊：
影响因子：
56.9
通讯作者：
PARKER, KL
中科院分区：
文献类型：
--
作者：
TRPIS, M;DUHRKOPF, RE;PARKER, KL
通常认为，昆虫媒介对医学上重要的病原体（如引起疟疾或丝虫病的病原体）的易感性或难治性的遗传模式遵循正常的孟德尔定律，并涉及一对等位基因。描述了证明蚊子对丝虫寄生虫易感性的另一种遗传模式的实验。在盾叶伊蚊复合体的易感种和难治种之间进行杂交，并测试杂交和回交后代对B感染的易感性。malayi和B. pahangi。遗传遵循非孟德尔模式，表明通过母本遗传的染色体外因素。
The mode of inheritance of susceptibility or refractoriness of insect-vectors to medically important pathogens such as those causing malaria or filariasis is usually believed to follow normal Mendelian laws and to involve a single pair of alleles. Experiments are described that demonstrate another mode of inheritance of mosquito susceptibility to filarial parasites. Crosses were made between susceptible and refractory species of the Aedes scutellaris complex and the hybrid and backcross progeny were tested for susceptibility to infection by B. malayi and B. pahangi. Inheritance follows a non-Mendelian pattern indicative of extrachromosomal factors inherited through the maternal parent.