Toward a minimally invasive bladder pressure monitoring system: Model bladder for in vitro testing
Toward a minimally invasive bladder pressure monitoring system: Model bladder for in vitro testing
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迈向微创膀胱压力监测系统：用于体外测试的膀胱模型
DOI：
10.1109/biorob.2010.5625981
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
B. Behkam
中科院分区：
文献类型：
--
作者：
J. N. Weaver;Julia C. Alspaugh;B. Behkam
泌尿系统疾病严重影响了美国1300万成年人的生活质量[1]。目前的诊断方法往往是不舒服和不确定的，为研究人员创造一个更好的诊断系统提供了动力。这项工作的重点是开发一种替代方法膀胱测压，尿动力学测试，收集压力数据。本文提出的设计是一个微型机器人压力传感系统，该系统连接到膀胱壁内部，在12 - 24小时内收集和无线传输压力数据。为了能够对微型传感装置进行测试，设计了一个模型泌尿系统。将模型膀胱并入模型泌尿系统中，并且整个系统已被提交压力测试以表征填充和排泄行为。系留压力传感器用于收集数据。在传统膀胱测压结果中看到的趋势和压力曲线被模型泌尿系统紧密地模仿，这导致得出以下结论：膀胱模型是收集压力数据并在缩放水平上模仿人类膀胱的可靠方式。所提出的微型机器人压力传感系统的设计和制造使用低功耗和低电流的组件。与自由浮动设计相比，11：5 mm × 17 mm × 8 mm（长×宽×厚）器械设计用于连接到膀胱壁，从而实现更准确的压力数据收集。传感系统将允许在患者的正常日常生活中无线捕获来自膀胱内部的所有范围的压力数据。所收集的压力数据有望比传统方法更有效地描绘典型的膀胱趋势，并导致更准确的尿失禁诊断。
Urinary Incontinence significantly affects the quality of life of 13 Million adults in America [1]. The current diagnosis methods are often uncomfortable and inconclusive, providing motivation for researchers to create a better diagnostic system. This work focuses on developing an alternative method for Cystometry, a Urodynamic test which collects pressure data. The design proposed in this paper is for a microrobotic pressure sensing system that is attached to the inside of the bladder wall to collect and wirelessly transmit pressure data over the period of 12–24 hours. In order to be able to test the miniature sensing device, a model urinary system was designed. A model bladder is incorporated into the model urinary system, and the whole system has been submitted to pressure tests to characterize filling and voiding behavior. A tethered pressure sensor was used to collect data. The trends and pressure profiles seen in traditional Cystometry results are closely mimicked by the model urinary system, which leads to the conclusion that the bladder model is a reliable way to collect pressure data and mimic a human bladder on a scaled level. The proposed microrobotic pressure sensing system has been designed and is to be fabricated using low power and low current components. The 11:5 mm × 17 mm × 8 mm (length×width×thickness) device is designed to be attached to the bladder wall versus a free floating designs, leading to a more accurate pressure data collection. The sensing system will allow all ranges of pressure data from inside the bladder to be captured wirelessly during a patient's normal daily routine. The collected pressure data is expected to depict typical bladder trends more efficiently than traditional methods and lead to more accurate diagnosis of incontinence.