Expression of extraocular-superfast-myosin heavy chain in rat laryngeal muscles.
Expression of extraocular-superfast-myosin heavy chain in rat laryngeal muscles.
复制标题
大鼠喉肌中眼外超快肌球蛋白重链的表达。
DOI：
10.1097/00001756-199811160-00015
复制
发表时间：
1998
期刊：
影响因子：
1.7
通讯作者：
Flint,PW
中科院分区：
文献类型：
--
作者：
Shiotani,A;Flint,PW
超快肌球蛋白重链（SUPERFAST myosin heavy chain， MHC）不仅存在于颌肌和眼外肌中，也存在于喉部肌肉中。采用抗EOM抗体免疫染色和Western blot方法对喉部肌肉中EOM MHC进行鉴定和定位。Western blot证实喉部il - MHC的特异性反应性，免疫染色显示甲状腺样腱肌外侧部纤维均与EOM抗体有反应。在甲状杓内侧、环杓后肌和环杓外侧肌可见散在分布的阳性纤维。环甲肌未检出EOM MHC。EOM MHC在大鼠喉肌中的表达与气道保护反射的功能需求一致。
SUPERFAST myosin heavy chain (MHC), which is found in jaw-closing muscle and extraocular muscle (EOM), may also be found in rat laryngeal muscles. Immunostaining and Western blot using anti-EOM antibody were performed to identify and localize EOM MHC in laryngeal muscles. Specific reactivity of laryngeal IIL MHC was confirmed by Western blot and on immunostaining, all fibers in the lateral part of thyroarytenoid muscle reacted with EOM antibody. A scattered pattern of positive fibers was observed in the medial part of the thyroarytenoid, the posterior cricoarytenoid and the lateral cricoarytenoid muscles. EOM MHC was not detected in the cricothyroid muscle. The expression of EOM MHC in rat laryngeal muscle is consistent with the functional demands of the airway protection reflex.