Prevalence of the metabolic syndrome across cardiorespiratory fitness levels in women
Prevalence of the metabolic syndrome across cardiorespiratory fitness levels in women
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DOI：
10.1038/oby.2004.99
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发表时间：
2004-05-01
期刊：
影响因子：
--
通讯作者：
Blair, SN
中科院分区：
文献类型：
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作者：
Farrell, SW;Cheng, YLJ;Blair, SN
目的：确定女性中各年龄层代谢综合征的患病率和心肺健康 (CRF) 水平。研究方法和程序：7104 名女性接受了体检，包括最大平板运动测试。参与者根据年龄分为 CRF 五分位数。代谢综合征是根据成人治疗小组 III 指南确定的。对 CRF 五分位数的人口变量以及 CRF 五分位数的代谢综合征患病率、年龄层和达到的最大工作量 [最大代谢当量 (MET) 水平] 进行了趋势测试。结果：代谢综合征的总体患病率为 6.5%。 CRF 五分位数的年龄和吸烟调整患病率较低（五分位数 I 至 V 分别为 19.0%、6.7%、6.0%、3.6% 和 2.3%，趋势 p = 0.001）。经吸烟调整后的代谢综合征患病率在各个年龄段均较高（20至29岁、30至39岁、40至49岁、50至59岁、60至69岁和70至80岁年龄层分别为2.4%、2.7%、6.4%、8.7%、15.3%和16.1%，p为趋势= 0.001）。达到最大 MET 水平或更高的女性在不同年龄组中代谢综合征的患病率是达到最大 MET 水平较低的女性的三分之一到四分之一。 讨论：在不同年龄层的女性中，随着 CRF 水平逐渐升高，代谢综合征的患病率明显降低。由于定期的体力活动可以改善代谢综合征的各个组成部分，因此在某些情况下，体能较差的女性中 CRF 的适度增加可能会改善代谢综合征。
Objective: To determine the prevalence of the metabolic syndrome across age strata and cardiorespiratory fitness (CRF) levels in women.Research Methods and Procedures: 7104 women underwent a physical examination, including a maximal treadmill exercise test. Participants were divided into CRF quintiles according to age. The metabolic syndrome was identified using Adult Treatment Panel-III Guidelines. Tests for trend were performed on demographic variables across CRF quintiles, as well as prevalence of the metabolic syndrome across CRF quintiles, age strata, and maximal workload achieved [maximal metabolic equivalent (MET) level].Results: The overall prevalence of the metabolic syndrome was 6.5%. Age- and smoking-adjusted prevalence was lower across quintiles of CRF (19.0%, 6.7%, 6.0%, 3.6%, and 2.3% for quintiles I to V, respectively, p for trend = 0.001). Smoking-adjusted prevalence of the metabolic syndrome was higher across age strata (2.4%, 2.7%, 6.4%, 8.7%, 15.3%, and 16.1 % for ages 20 to 29, 30 to 39, 40 to 49, 50 to 59, 60 to 69, and 70 to 80, respectively, p for trend = 0.001). Prevalence of the metabolic syndrome in the different age groups for women who achieved a maximal MET level of I I or higher was one-third to one-fourth that of women who achieved lower maximal MET levels.Discussion: Prevalence of the metabolic syndrome was markedly lower across progressively higher levels of CRF in women of different age strata. Because regular physical activity improves components of the metabolic syndrome, modest increases in CRF among low fit women may ameliorate the metabolic syndrome in some instances.