Oxygen delivery through high-flow nasal cannulae increase end-expiratory lung volume and reduce respiratory rate in post-cardiac surgical patients
Oxygen delivery through high-flow nasal cannulae increase end-expiratory lung volume and reduce respiratory rate in post-cardiac surgical patients
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DOI：
10.1093/bja/aer265
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发表时间：
2011-12-01
影响因子：
9.8
通讯作者：
Fraser, J. F.
中科院分区：
文献类型：
--
作者：
Corley, A.;Caruana, L. R.;Fraser, J. F.
背景高流量鼻插管（HFNCs）可产生口咽气道正压，但尚不清楚其使用如何影响肺容量。电阻抗断层扫描允许通过测量肺阻抗的变化来评估肺容量的变化。主要目的是研究HFNC对气道压力（Paw）和呼气末肺容积（EELV）的影响，并确定两者之间的任何相关性。次要目的是研究HFNC对呼吸频率、呼吸困难、潮气量和氧合的影响;以及BMI和EELV之间的相互作用。对20例心脏手术后处方HFNC的患者进行了研究。首先记录低流量氧疗时的阻抗测量值、P-aw、Pa-o2/FIo 2比值、呼吸频率和改良的博格评分，然后记录HFNC。Paw与呼气末肺阻抗（EELI）呈显著正相关（r=0.7，P
Background. High-flow nasal cannulae (HFNCs) create positive oropharyngeal airway pressure, but it is unclear how their use affects lung volume. Electrical impedance tomography allows the assessment of changes in lung volume by measuring changes in lung impedance. Primary objectives were to investigate the effects of HFNC on airway pressure (Paw) and end-expiratory lung volume (EELV) and to identify any correlation between the two. Secondary objectives were to investigate the effects of HFNC on respiratory rate, dyspnoea, tidal volume, and oxygenation; and the interaction between BMI and EELV.Methods. Twenty patients prescribed HFNC post-cardiac surgery were investigated. Impedance measures, P-aw, Pa-o2/FIo2 ratio, respiratory rate, and modified Borg scores were recorded first on low-flow oxygen and then on HFNC.Results. A strong and significant correlation existed between Paw and end-expiratory lung impedance (EELI) (r=0.7, P