Nuclear magnetic resonance imaging of the cardiovascular system: normal and pathologic findings.
Nuclear magnetic resonance imaging of the cardiovascular system: normal and pathologic findings.
复制标题
心血管系统的核磁共振成像：正常和病理结果。
DOI：
10.1148/radiology.147.3.6601813
复制
发表时间：
1983
期刊：
影响因子：
19.7
通讯作者：
Kaufman,L
中科院分区：
文献类型：
--
作者：
Herfkens,RJ;Higgins,CB;Hricak,H;Lipton,MJ;Crooks,LE;Lanzer,P;Botvinick,E;Brundage,B;Sheldon,PE;Kaufman,L
在244名志愿者和患者的早期临床试验中，使用3.5 KGauss（0.35 T）装置进行了心血管系统的全身核磁共振（NMR）成像。采用多参数自旋回波技术。血管与实体器官和病变明显区分开来，因为在正常速度的层流中很少或没有看到管腔内信号，而实体器官产生更强烈的图像。在正常患者中观察到特征性血流信号，并通过改变成像参数而加重。部分患者在非造影图像上心腔轮廓清晰。在一个病例中，心室的内部地形图在门控图像上显示得很好。腔内病变，如主动脉夹层，主动脉瘤和左心室，主动脉粥样硬化，清楚地表明。显示冠状动脉旁路移植物通畅。由于缓慢或湍流的异常流动模式在使用第二自旋回波的图像上被加重。这一初步经验表明，相当大的潜力，核磁共振成像在心血管疾病的评价。
Whole body nuclear magnetic resonance (NMR) imaging of the cardiovascular system was carried out in early clinical trials in 244 volunteers and patients using a 3.5 KGauss (0.35 T) unit. The spin echo technique with multiple imaging parameters was used. Blood vessels were clearly discriminated from solid organs and lesions because little or no intraluminal signal is seen with laminar blood flow at normal velocities, whereas a more intense image is generated by solid organs. Characteristic flow signals were observed in normal patients and were accentuated by varying the imaging parameters. Cardiac chambers were well delineated in some patients on nongated images. In one case, internal topography of the ventricles was exquisitely displayed on a gated image. Intraluminal pathology, such as dissection of the aorta, aneurysms of the aorta and left ventricle, and aortic atheroma, was clearly demonstrated. Patency of coronary arterial bypass grafts was shown. Abnormal flow patterns due to slow or turbulent flow were accentuated on images using the second spin echo. This preliminary experience indicates the considerable potential of NMR imaging in the evaluation of cardiovascular diseases.