Target-induced strand release (TISR) from aptamer-DNA duplex: A general strategy for electronic detection of biomolecules ranging from a small molecule to a large protein
Target-induced strand release (TISR) from aptamer-DNA duplex: A general strategy for electronic detection of biomolecules ranging from a small molecule to a large protein
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DOI：
10.1039/b719089c
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发表时间：
2008-01-01
期刊：
影响因子：
4.2
通讯作者：
Yamana, Kazushige
中科院分区：
文献类型：
--
作者：
Yoshizumi, Jyun;Kumamoto, Satoshi;Yamana, Kazushige
我们描述了一种基于电子适体的生物传感器的一般策略，该策略基于从结合在电极上的适体捕获DNA双链体中靶诱导氧化还原修饰的适体的链释放（TISR）。
We describe a general strategy for electronic aptamer-based biosensor that is based on target-induced strand release (TISR) of a redox-modified aptamer from the aptamer-capture DNA duplex bound on an electrode.