Sex-related differences in migraine
Sex-related differences in migraine
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DOI：
10.1007/s10072-014-1772-y
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发表时间：
2014-05-01
影响因子：
3.3
通讯作者：
Strada, Laura
中科院分区：
文献类型：
--
作者：
Finocchi, Cinzia;Strada, Laura
本文综述了偏头痛流行病学、症状、自然病程和共病性疾病的性别差异。偏头痛在女性中是男性的两倍多，女性经历更频繁，更持久和更痛苦的发作，有更多的残疾和从发作性偏头痛转变为慢性偏头痛的风险大于男性，但这些差异背后的机制仍然知之甚少。性激素的作用，基因，以及大脑功能和结构的差异进行了讨论。最后，我们评估了许多与女性偏头痛治疗有关的性别问题。在今后的研究中，应分别分析男女的数据，以确保能够确定两性之间的差异。
This paper reviews sex-related differences in migraine epidemiology, symptoms, natural history and co-morbid disorders. Migraine is more than twice as common in females as in males, and women experience more frequent, longer lasting and more painful attacks, have more disability and a risk of transition from episodic to chronic migraine greater than men, but the mechanisms behind these differences are still poorly understood. The role of sex hormones, genes, and the differences in brain function and structure are discussed. Finally, we evaluate the many gender-related questions about treatment of migraine in women. In future research data should be analyzed separately for men and women to ensure that differences between the sexes could be identified.