Recurrence of major depression in adolescence and early adulthood, and later mental health, educational and economic outcomes

Recurrence of major depression in adolescence and early adulthood, and later mental health, educational and economic outcomes
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DOI:
10.1192/bjp.bp.107.036079
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发表时间:
2007-10-01
影响因子:
10.5
通讯作者:
Horwood, L. John
Horwood, L. John
中科院分区:
医学1区
文献类型:
--
作者:
Fergusson, David M.;Boden, Joseph M.;Horwood, L. John

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背景目前尚不清楚青少年抑郁症的复发如何影响以后的生活outcomesAims要检查之间的关联,在年龄16-21岁的抑郁症的频率和以后的结果,之前和之后控制潜在的混杂factors.Method数据收集从一个25年的纵向研究出生队列的新西兰儿童(n=982)。结果16-21岁抑郁症的发生率与各指标之间均存在显著性相关(P < 0.05)。结果16-21岁抑郁症的发生率与各指标之间均存在显著性相关(P < 0.05)。在调整混杂因素后,抑郁发生率与心理健康状况、福利依赖和失业率之间的相关性仍然显著(P < 0.05)。结论青少年和青年期抑郁发生率与青年期不良心理健康状况和经济状况有关。
Background It is unclear how the recurrence of major depression in adolescence affects later life outcomesAims To examine the associations between the frequency of major depression at ages 16-21 and later outcomes, both before and after controlling for potentially confounding factors.Method Data were gathered from a 25-year longitudinal study of a birth cohort of New Zealand children (n=982). Outcome measures included DSM-IV symptom criteria for major depression and anxiety disorders, suicidal ideation and attempted suicide, achieving university degree or other tertiary education qualification, welfare dependence and unemployment, and income at ages 21-25 years.Results There were significant (P < 0.05) associations between the frequency of depression at ages 16-21 years and all outcome measures. After adjustment for confounding factors, the association between frequency of depression and all mental health outcomes, and welfare dependence and unemployment, remained significant (P < 0.05).Conclusions The frequency of depression in adolescence and young adulthood is associated with adverse mental health and economic outcomes in early adulthood.