Construction of an anthropopathic abdominal phantom for accuracy validation of deformable image registration.

Construction of an anthropopathic abdominal phantom for accuracy validation of deformable image registration.
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构建拟人化腹部模型,以验证可变形图像配准的准确性。

DOI:
10.3233/thc-161200
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发表时间:
2016
期刊:
Technology and health care : official journal of the European Society for Engineering and Medicine
影响因子:
--
通讯作者:
X. Zhen
X. Zhen
中科院分区:
--
文献类型:
--
作者:
Y. Liao;H. Chen;L. Zhou;X. Zhen

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本研究的目的是设计并制作一个用于自适应放射治疗中形变图像配准算法准确性评价的腹部模型。所构建的可变形器官,包括肝、肾、脾和胃,由聚氯乙烯(PVC)和软化剂对苯二甲酸二辛酯的混合物制成,而刚性结构,即椎骨,由白色水泥制成。研究了PVC-柔软剂共混比与器官CT值的关系,并采用三维打印技术制作了具有高度亲水性的器官。详细介绍了体模的构建步骤、标志点的放置、体模成分的选择和构建方法。制造的器官的机械性能的初步结果也被提出。实验结果表明,所构建的体模具有良好的弹性特性和与人体器官接近的CT值,可用于模拟真实的腹部器官变形,验证三维重建算法的几何精度。
The purpose of this study is to design and fabricate an anthropopathic abdominal phantom for accuracy evaluation of deformable image registration (DIR) algorithms in adaptive radiation therapy. The constructed deformable organs, including the liver, kidney, spleen and stomach, are made of mixture of polyvinyl chloride (PVC) and softener dioctyl terephthalate, while the rigid structures, i.e. vertebrae, are made of white cement. Relation between the PVC-softener blending ratio and organ CT number is studied, and three-dimensional printing technic is employed to create highly anthropopathic organs in terms of organ shape and density. Detailed steps for phantom construction, landmark point placement and choice of phantom ingredients and construction recipe are introduced. Preliminary results of the mechanical properties of the fabricated organs are also presented. The experimental results indicate that the constructed phantom has satisfactory elastic characteristics and close CT number with corporal organs, and can potentially be applied to simulate real abdominal organ deformation in geometric accuracy validation of DIR algorithms.
DOI: 10.1118/1.2739812
发表时间: 2007-07-01
期刊: MEDICAL PHYSICS
影响因子: 3.8
作者:
Kashani, Rojano;Hub, Martina;Balter, James M.
通讯作者: Balter, James M.