Cytochrome c Oxidase: TWO Models
Cytochrome c Oxidase: TWO Models
复制标题
细胞色素 c 氧化酶:两种模型
DOI:
--
复制
发表时间:
1983
影响因子:
--
通讯作者:
W. W. Wainio
中科院分区:
文献类型:
--
作者:
W. W. Wainio
Cytochrome c oxidase is an enzyme present in the inner membrane of the mitochondrion where it functions as the terminal carrier in the electron transferring sequence known as the respiratory chain. Cytochrome c oxidase oxidizes ferrocytochrome c and is itself oxidized by dioxygen. Following the addition of four protons, the products of the reduction of one molecule of dioxygen are two molecules of water. Cytochrome c oxidase (EC I . 9 . 3 . I ) is the name given to the complete enzyme complex. The two-enzyme hypothesis proposed by Keilin & Hartree (1939) supports the concept that oxidase consists of cytochrome a and cytochrome a3. Cytochrome a3 is considered to be the dioxygenand carbon monoxide-reactive part of the molecule, and Cu, its associated copper. Cu, should, therefore, be associated with cytochrome a. Recently, Saraste, Penttila & Wikstrom (1981) have reported that the minimum molecular weight (per haem or per copper) of cytochrome c oxidase is about 50000 daltons. From this result it appears that the monomer of the enzyme, i.e. that protein unit which contains one each of six or seven protein subunits and has a size of I 10000
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DOI:
--
发表时间:
1981
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
Stevens,TH;Chan,SI
通讯作者:
Chan,SI
影响因子:
3.4
作者:
Powers,L;Chance,B;Ching,Y;Angiolillo,P
通讯作者:
Angiolillo,P
影响因子:
2.9
作者:
BRUDVIG, GW;STEVENS, TH;CHAN, SI
通讯作者:
CHAN, SI
DOI:
10.1073/pnas.78.3.1652
发表时间:
1981
影响因子:
11.1
作者:
Carter,KR;Antalis,TM;Palmer,G;Ferris,NS;Woodruff,WH
通讯作者:
Woodruff,WH
DOI:
10.1073/pnas.78.3.1456
发表时间:
1981
影响因子:
11.1
作者:
Vik,SB;Georgevich,G;Capaldi,RA
通讯作者:
Capaldi,RA