Alternative Splicing in Plant Genes: A Means of Regulating the Environmental Fitness of Plants.
Alternative Splicing in Plant Genes: A Means of Regulating the Environmental Fitness of Plants.
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植物基因的选择性剪接：调节植物环境适应性的一种手段
DOI：
10.3390/ijms18020432
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发表时间：
2017-02-20
影响因子：
5.6
通讯作者：
Ma L
中科院分区：
文献类型：
--
作者：
Shang X;Cao Y;Ma L
基因表达可以通过转录和转录后机制来调节。真核生物中的转录产生前mRNA分子，其在转录后被加工和剪接以产生可翻译的mRNA。通过选择性剪接（AS），可以从单个前体mRNA产生多于一种mRNA;因此，AS用于使生物体的转录组和蛋白质组多样化。以往对植物基因表达的研究主要集中在转录调控在响应环境变化中的作用。然而，最近的数据表明，转录后调节，特别是AS，是必要的植物适应不断变化的环境。在这篇综述中，我们总结了我们的理解AS在植物发育过程中响应环境变化的最新进展。我们认为选择性基因剪接是一种调节植物环境适应性的新方法。
Gene expression can be regulated through transcriptional and post-transcriptional mechanisms. Transcription in eukaryotes produces pre-mRNA molecules, which are processed and spliced post-transcriptionally to create translatable mRNAs. More than one mRNA may be produced from a single pre-mRNA by alternative splicing (AS); thus, AS serves to diversify an organism’s transcriptome and proteome. Previous studies of gene expression in plants have focused on the role of transcriptional regulation in response to environmental changes. However, recent data suggest that post-transcriptional regulation, especially AS, is necessary for plants to adapt to a changing environment. In this review, we summarize recent advances in our understanding of AS during plant development in response to environmental changes. We suggest that alternative gene splicing is a novel means of regulating the environmental fitness of plants.