A 75-ch SQUID Biomagnetometer System for Human Cervical Spinal Cord Evoked Field

A 75-ch SQUID Biomagnetometer System for Human Cervical Spinal Cord Evoked Field
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用于人体颈脊髓诱发场的 75 通道 SQUID 生物磁力计系统

DOI:
10.1109/tasc.2007.910152
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发表时间:
2007
影响因子:
1.8
通讯作者:
S. Kawabata
S. Kawabata
中科院分区:
物理与天体物理3区
文献类型:
--
作者:
Y. Adachi;J. Kawai;G. Uehara;M. Miyamoto;S. Tomizawa;S. Kawabata

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为了对脊髓进行无创性功能诊断,研制了一套75通道SQUID生物磁测量系统,用于测量颈髓诱发磁场(SCEF)。传感器阵列具有25个SQUID矢量传感器,这些SQUID矢量传感器沿着圆柱形表面布置以适应受试者颈部的形状。在80 mm × 90 mm的区域内同时观察到磁场,不仅在受试者体表的径向方向上,而且在切向方向上。杜瓦瓶具有独特的形状,具有圆柱形主体和从其侧面突出的突起。传感器阵列安装在突出部分中。该设计被优化以检测坐在斜倚位置的受试者的颈部后部处的磁信号。我们应用所开发的SQUID系统测量正常受试者的颈部SCEF,这些受试者被给予电脉冲刺激他们的正中神经在手腕处。在所有受试者的颈部均成功检测到诱发的磁信号。作为可重复的结果,观察到SCEF分布的特征性模式的过渡,并且在随时间变化的SCEF分布中发现了沿脊髓沿着传播的信号分量。我们期望对传播信号成分的研究将有助于建立脊髓的非侵入性功能诊断。
A 75-ch SQUID biomagnetometer system for the measurement of the cervical spinal cord evoked magnetic field (SCEF) was developed for the purpose of the noninvasive functional diagnosis of the spinal cord. The sensor array has 25 SQUID vector sensors arranged along the cylindrical surface to fit to the shape of the subject's neck. The magnetic fields, not only in the direction radial to the subject's body surface but also in the tangential direction, are observed in the area of 80 mm times 90 mm at one time. The dewar has a unique shape with a cylindrical main body and a protrusion from its side surface. The sensor array is installed in the protruded part. This design is optimized to detect magnetic signals at the back of the neck of the subject sitting in a reclining position. We applied the developed SQUID system to the cervical SCEF measurement of normal subjects who were given electric pulse stimulation to their median nerves at the wrists. The evoked magnetic signals were successfully detected at the cervixes of all subjects. A characteristic pattern of transition of the SCEF distribution was observed as a reproducible result and the signal components propagating along the spinal cord were found in the time varying SCEF distribution. We expect that the investigation of the propagating signal components would help to establish a noninvasive functional diagnosis of the spinal cord.
针对斜躺受试者进行优化的 30 通道 SQUID 矢量生物磁力计系统
DOI: --
发表时间: 2005
期刊: IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY 15
影响因子: --
作者:
Adachi Y;et al.
通讯作者: et al.