Malignant melanoma: Incidence issues and their effect on diagnosis and treatment in the 1990s
Malignant melanoma: Incidence issues and their effect on diagnosis and treatment in the 1990s
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DOI：
10.4065/72.4.367
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发表时间：
1997-04-01
影响因子：
8.9
通讯作者：
Rigel, DS
中科院分区：
文献类型：
--
作者：
Rigel, DS
在美国和全世界，黑色素瘤的发病率以比任何其他癌症更快的速度增加。几个因素表明，这种发病率的增加是真实的，而不是由于人为因素。这种快速增加并不归因于癌症病例的更好的总体计数（因为其他癌症的发病率正在下降）。此外，这不是由于组织学标准的变化。最后，在存活率也增加的同时，来自黑素瘤的死亡率继续增加。只有当实际发病率以甚至比死亡率更快的速率增加时，这种明显的矛盾才是真实的。黑素瘤发病率的这种急剧增加突出了对改进预防、诊断、并且作为黑素瘤的治疗作为公共卫生问题变得越来越重要。
The incidence of melanoma is increasing at a rate faster than that for any other cancer in the United States and worldwide, Several factors show that this increase in incidence is real and not due to artifact, The rapid increase is not attributable to better overall counting of the cases of cancer (because the incidence of other cancers is decreasing). Furthermore, it is not due to changes in histologic criteria, Finally, the mortality rate from melanoma continues to increase at a time when survival rates are also increasing, This apparent paradox can be true only if the actual incidence is increasing at an even faster rate than the death rate, This dramatic increase in the incidence of melanoma highlights the need for improved methods of prevention, diagnosis, and treatment as melanoma becomes increasingly important as a public health issue.