Myocardial stunning demonstrated with rest and post-stress measurements of left ventricular function using dual-isotope gated myocardial perfusion SPECT
Myocardial stunning demonstrated with rest and post-stress measurements of left ventricular function using dual-isotope gated myocardial perfusion SPECT
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DOI：
10.1097/01.mnm.0000126510.81093.02
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发表时间：
2004-07-01
影响因子：
1.5
通讯作者：
Tamir, A
中科院分区：
文献类型：
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作者：
Ben-Haim, S;Gips, S;Tamir, A
目的 我们通过双同位素门控心肌灌注 SPECT (GMPS) 评估静息 (REF) 和应激后 (SEF) 时的左心室射血分数 (LVEF)，静息时注射 Tl-201，峰值应激时注射 Tc-99m 司他米比 (Tc-99m-MIBI)，以评估应激后致昏的发生。方法 连续 236 例患者在静息和应激后进行 GMPS。使用 GMPS 的 17 段模型分析计算总压力和休息分数以及总差异分数 (SDS)。 SDS >3 表明存在严重缺血。自动生成 REF 和 SEF，并计算 DEF (SEF-REF)。结果 在 103 名患者 (44%) 中观察到明显的应激诱发缺血。 REF 为 54.72% +/- 15.75%，SEF 为 55.69% +/- 16.65%（P
Objectives We have evaluated left ventricular ejection fraction (LVEF) at rest (REF) and after stress (SEF) with dual-isotope gated myocardial perfusion SPECT (GMPS) with Tl-201 injected at rest and Tc-99m sestamibi (Tc-99m-MIBI) injected at peak stress, to assess the occurrence of post-stress stunning.Methods Two hundred and thirty-six consecutive patients had GMPS at rest and post-stress. The summed stress and rest scores and the summed difference score (SDS) were calculated using a 17-segment model analysis of GMPS. An SDS >3 indicated significant ischaemia. The REF and SEF were automatically generated and the DEF (SEF-REF) was calculated.Results Significant stress induced ischaemia was observed in 103 patients (44%). REF was 54.72% +/- 15.75% and SEF was 55.69% +/- 16.65% (P