Nucleotide sequences of segments 1, 3 and 4 of the genome of Bombyx mori cypovirus 1 encoding putative capsid proteins VP1, VP3 and VP4, respectively
Nucleotide sequences of segments 1, 3 and 4 of the genome of Bombyx mori cypovirus 1 encoding putative capsid proteins VP1, VP3 and VP4, respectively
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DOI：
10.1099/0022-1317-83-6-1477
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发表时间：
2002-06-01
影响因子：
3.8
通讯作者：
Carner, GR
中科院分区：
文献类型：
--
作者：
Hagiwara, K;Rao, SJ;Carner, GR
测定了家蚕隐蔽病毒I型(BmCPV-1)基因组片段S1、S3和S4的全序列。该片段由4190、3846和3262个核苷酸组成，编码1333、1239和1058个氨基酸，分子质量分别为148、140和120 kDa(分别为p148、p140和p120)。所有片段都有一个单一的开放阅读框架。同源性搜索表明，这三种蛋白都与呼肠孤病毒科水稻矮化病毒属的成员水稻碎屑矮化病毒的蛋白同源。P140与其他病毒结构蛋白的部分同源性也被发现。根据预测的分子质量以及与其他病毒结构蛋白的同源性，我们认为S1、S3和S4分别编码BmCPV-1的衣壳蛋白VP1、VP3和VP4。
The complete nucleotide sequences of genomic segments S1, S3 and S4 from Bombyx mori cypo-virus I (BmCPV-1) have been determined. The segments consisted of 4190, 3846 and 3262 nucleotides encoding putative proteins of 1333, 1239 and 1058 amino acids with molecular masses of approximately 148, 140 and 120 kDa (p 148, p140 and p120, respectively). All segments possess a single open reading frame. Homology searches showed that all three proteins have homologies to proteins of Rice ragged stunt virus, a member of the genus Oryzavirus within the family Reoviridae. Partial homologies of p140 to structural proteins in other viruses were also found. The predicted molecular masses and the homologies with structural proteins in other viruses lead us to suggest that S1, S3 and S4 encode the capsid proteins VP1, VP3, and VP4, respectively, of BmCPV-1.