Survey of prescriptions for peptic ulcer drugs (ACT class AOB2) in Iceland.
Survey of prescriptions for peptic ulcer drugs (ACT class AOB2) in Iceland.
复制标题
冰岛消化性溃疡药物（ACT 类别 AOB2）处方调查。
DOI：
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发表时间：
1994
影响因子：
1.9
通讯作者：
B. Thjódleifsson
中科院分区：
文献类型：
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作者：
H. Thors;H. Sigurdsson;E. Oddsson;B. Thjódleifsson
背景
冰岛消化性溃疡药物的消费量为20 DDD/1000/天，是其他斯堪的纳维亚国家的两到三倍。这项研究的目的是记录使用模式，并可能找出高消费的原因。
方法
1991年，冰岛对消化性溃疡药物（ACT类别AO2B）处方进行了为期1个月的调查。冰岛所有药房都参与了这项研究，获得了约90%在医院外使用的消化性溃疡药物的信息。药剂师登记了所有消化性溃疡药物的处方，包括患者的年龄和性别、处方医生的专业以及药物的名称、剂量和数量。
结果
共登记处方2021张，占15.4 DDD/1000/天。消化性溃疡药物使用率为1.52%，其中女性使用率为52.5%。 70-79 岁年龄段使用率最高，为 2.91%。 H2阻滞剂占79%，奥美拉唑占17%，其他药物占4%。 65% 的药物由全科医生开出，胃肠科医生开出 15%，其他专科医生开出 14%。如果患者自己取药，则要求他填写一份调查问卷，内容涉及处方原因、以前的处方和调查。共收到 1131 份（56%）患者问卷。只有1%的患者不知道处方原因。患者登记的处方中，30%用于治疗消化性溃疡，29%用于治疗胃灼热，21%用于治疗胃炎，9%用于治疗消化不良，7%用于预防其他药物的副作用。据数据估计，约40%的处方是治疗非溃疡性消化不良。对 67% 的患者进行了调查，但 33% 的患者在与医生预约后才收到处方。
结论
调查结果提示，冰岛消化性溃疡药物的大量使用主要是由于非溃疡性消化不良的过度使用。
BACKGROUND
The consumption of peptic ulcer drugs in Iceland is 20 DDD/1000/day, which is two to three times higher than in other Scandinavian countries. This study was done to register the pattern of use and possibly to find reasons for the high consumption.
METHODS
Prescriptions for peptic ulcer drugs (ACT class AO2B) were surveyed in Iceland during 1 month in 1991. All pharmacies in Iceland participated in the study, and information was obtained on about 90% of peptic ulcer drugs used outside hospitals. The pharmacists registered all prescriptions of peptic ulcer drugs with regard to the age and sex of the patient, speciality of the prescribing physician, and name, dose, and quantity of the drug.
RESULTS
A total of 2021 prescriptions were registered, accounting for 15.4 DDD/1000/day. The prevalence of peptic ulcer drug use was 1.52%, but female use was 52.5%. The maximal use, 2.91% was in the age group 70-79 years. H2 blockers accounted for 79%, omeprazole for 17%, and other drugs for 4%. General practitioners prescribed 65% of the drugs, gastroenterologists 15%, and other specialists 14%. If the patient himself collected the drug, he was asked to fill out a questionnaire with regard to the reason for the prescription, previous prescriptions, and investigations. A total of 1131 (56%) of patient questionnaires were received. Only 1% of the patients did not know the reason for the prescription. The patients registered that 30% of the prescriptions were for peptic ulcer, 29% for heartburn, 21% for gastritis, 9% for dyspepsia, and 7% for prevention of side effects of other drugs. It was estimated from the data that about 40% of the prescriptions were for non-ulcer dyspepsia. Investigations were done in 67% of the patients, but 33% received the prescription only after an appointment with a physician.
CONCLUSIONS
The results of the survey suggest that the extensive use of peptic ulcer drugs in Iceland is mostly due to excessive use in non-ulcer dyspepsia.
消化性溃疡的住院率和死亡率：大型健康维护组织与美国数据的比较。
影响因子：
29.4
作者：
Kurata,JH;Honda,GD;Frankl,H
通讯作者：
Frankl,H