Effects of coronary-artery bypass on global and regional left ventricular function during exercise.
Effects of coronary-artery bypass on global and regional left ventricular function during exercise.
复制标题
冠状动脉搭桥术对运动期间整体和局部左心室功能的影响。
DOI：
10.1056/nejm197806292982602
复制
发表时间：
1978
期刊：
影响因子：
--
通讯作者：
S. Epstein
中科院分区：
文献类型：
--
作者：
K. Kent;J. Borer;M. Green;S. Bacharach;C. Mcintosh;D. Conkle;S. Epstein
为了确定冠状动脉血运重建对运动引起的左心室射血分数和局部收缩异常的影响，我们获得了 23 名连续患者术前和术后心电图门控 99mTc 放射性核素电影血管造影照片。休息时，他们的平均射血分数保持不变：51 +/- 3% vs 54 +/- 4% (+/- S.E.M.)。然而，其中 17 名患者在术后运动期间射血分数有所改善（增加 51%）。其余六名患者在运动过程中射血分数没有变化或降低。所有在运动期间射血分数改善的患者的症状均得到改善。休息时区域功能没有改善，但运动引起的功能障碍区域确实有所改善。尽管冠状动脉血运重建对静息时的左心室功能影响不大，但大多数症状改善的患者运动时的射血分数和运动引起的室壁运动异常有所改善。
To determine the effect of coronary revascularization on exercise-induced abnormalities of left ventricular-ejection fraction and regional contraction, we obtained electrocardiograph-gated 99mTc radionuclide cineangiograms before and after operation in 23 consecutive patients. At rest, their average ejection fraction remained unchanged: 51 +/- 3 versus 54 +/- 4 per cent (+/- S.E.M.). However, 17 of the patients showed improvement of ejection fraction during postoperative exercise (increase of 51 per cent). The remaining six patients had no change or a decreased ejection fraction during exercise. All patients with improved ejection fractions during exercise were symptomatically improved. No improvement of regional function occurred at rest, but improvement did occur in regions of exercise-induced dysfunction. Although coronary revascularization has little effect on left ventricular function at rest, the ejection fraction during exercise and exercise-induced wall-motion abnormalities improve in most patients who experience symptomatic improvement.